ENSG00000162739


Homo sapiens

Features
Gene ID: ENSG00000162739
  
Biological name :SLAMF6
  
Synonyms : Q96DU3 / SLAMF6 / SLAM family member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 160485030
Gene end: 160523262
  
Corresponding Affymetrix probe sets: 1552497_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357034
Ensembl peptide - ENSP00000357036
Ensembl peptide - ENSP00000357038
NCBI entrez gene - 114836     See in Manteia.
OMIM - 606446
RefSeq - XM_017000217
RefSeq - NM_001184714
RefSeq - NM_001184715
RefSeq - NM_001184716
RefSeq - NM_052931
RefSeq - XM_017000215
RefSeq - XM_017000216
RefSeq Peptide - NP_443163
RefSeq Peptide - NP_001171643
RefSeq Peptide - NP_001171644
RefSeq Peptide - NP_001171645
swissprot - Q96DU3
Ensembl - ENSG00000162739
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9ET39ENSMUSG00000015314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NQ25 / SLAMF7 / SLAM family member 7ENSG0000002675127
CD84 / Q9UIB8 / CD84 moleculeENSG0000006629426
LY9 / Q9HBG7 / lymphocyte antigen 9ENSG0000012222425
Q96A28 / SLAMF9 / SLAM family member 9ENSG0000016272323


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IMP
 biological_processGO:0032740 positive regulation of interleukin-17 production IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045954 positive regulation of natural killer cell mediated cytotoxicity IDA
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0072540 T-helper 17 cell lineage commitment IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000183918 O60880 / SH2D1A / SH2 domain containing 1A  / complex / reaction
 ENSG00000198574 O14796 / SH2D1B / SH2 domain containing 1B  / complex / reaction
 ENSG00000162739 Q96DU3 / SLAMF6 / SLAM family member 6  / reaction / complex






 

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