ENSG00000198574


Homo sapiens

Features
Gene ID: ENSG00000198574
  
Biological name :SH2D1B
  
Synonyms : O14796 / SH2D1B / SH2 domain containing 1B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 162395266
Gene end: 162412138
  
Corresponding Affymetrix probe sets: 1553176_at (Human Genome U133 Plus 2.0 Array)   1553177_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356906
NCBI entrez gene - 117157     See in Manteia.
OMIM - 608510
RefSeq - NM_053282
RefSeq Peptide - NP_444512
swissprot - O14796
Ensembl - ENSG00000198574
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-264p11.1ENSDARG00000091835Danio rerio
 SH2D1BENSGALG00000028448Gallus gallus
 Q45HK4ENSMUSG00000073494Mus musculus
 Sh2d1b1ENSMUSG00000102418Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60880 / SH2D1A / SH2 domain containing 1AENSG0000018391836


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR035049  EAT-2, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002366 leukocyte activation involved in immune response ISS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002717 positive regulation of natural killer cell mediated immunity ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response ISS
 biological_processGO:0050776 regulation of immune response TAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030674 protein binding, bridging TAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000162739 Q96DU3 / SLAMF6 / SLAM family member 6  / complex / reaction






 

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© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr