ENSG00000067057


Homo sapiens

Features
Gene ID: ENSG00000067057
  
Biological name :PFKP
  
Synonyms : PFKP / phosphofructokinase, platelet / Q01813
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p15.2
Gene start: 3066333
Gene end: 3137712
  
Corresponding Affymetrix probe sets: 201037_at (Human Genome U133 Plus 2.0 Array)   240202_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410275
Ensembl peptide - ENSP00000408858
Ensembl peptide - ENSP00000476311
Ensembl peptide - ENSP00000477128
Ensembl peptide - ENSP00000370462
Ensembl peptide - ENSP00000370465
Ensembl peptide - ENSP00000370517
Ensembl peptide - ENSP00000385880
Ensembl peptide - ENSP00000387871
NCBI entrez gene - 5214     See in Manteia.
OMIM - 171840
RefSeq - NM_001323068
RefSeq - NM_001242339
RefSeq - NM_001323067
RefSeq - NM_001323069
RefSeq - NM_001323070
RefSeq - NM_001323071
RefSeq - NM_001323072
RefSeq - NM_001323073
RefSeq - NM_001323074
RefSeq - NM_001345944
RefSeq - NM_002627
RefSeq - XM_005252465
RefSeq - XM_005252466
RefSeq - XM_005252467
RefSeq - XM_006717449
RefSeq Peptide - NP_001229268
RefSeq Peptide - NP_001309996
RefSeq Peptide - NP_001309997
RefSeq Peptide - NP_001309998
RefSeq Peptide - NP_001309999
RefSeq Peptide - NP_001310000
RefSeq Peptide - NP_001310001
RefSeq Peptide - NP_001310002
RefSeq Peptide - NP_001310003
RefSeq Peptide - NP_001332873
RefSeq Peptide - NP_002618
swissprot - Q01813
swissprot - Q5VSR5
swissprot - B1APP8
swissprot - H0Y3Y3
swissprot - H0Y757
swissprot - V9GY25
swissprot - V9GYV7
swissprot - B1APP6
Ensembl - ENSG00000067057
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pfkpaENSDARG00000028000Danio rerio
 pfkpbENSDARG00000012801Danio rerio
 PFKPENSGALG00000006939Gallus gallus
 PfkpENSMUSG00000021196Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PFKM / P08237 / phosphofructokinase, muscleENSG0000015255665
PFKL / P17858 / phosphofructokinase, liver typeENSG0000014195963


Protein motifs (from Interpro)
Interpro ID Name
 IPR000023  Phosphofructokinase domain
 IPR009161  ATP-dependent 6-phosphofructokinase, eukaryotic-type
 IPR015912  Phosphofructokinase, conserved site
 IPR022953  ATP-dependent 6-phosphofructokinase
 IPR035966  Phosphofructokinase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006002 fructose 6-phosphate metabolic process IEA
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0061615 glycolytic process through fructose-6-phosphate IEA
 biological_processGO:0061621 canonical glycolysis TAS
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003872 6-phosphofructokinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141959 PFKL / P17858 / phosphofructokinase, liver type  / complex
 ENSG00000067057 PFKP / Q01813 / phosphofructokinase, platelet  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr