ENSMUSG00000021196


Mus musculus

Features
Gene ID: ENSMUSG00000021196
  
Biological name :Pfkp
  
Synonyms : ATP-dependent 6-phosphofructokinase, platelet type / Pfkp / Q9WUA3
  
Possible biological names infered from orthology : phosphofructokinase, platelet / Q01813
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A1
Gene start: 6579768
Gene end: 6648777
  
Corresponding Affymetrix probe sets: 10407481 (MoGene1.0st)   1416069_at (Mouse Genome 430 2.0 Array)   1430634_a_at (Mouse Genome 430 2.0 Array)   1437759_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117030
Ensembl peptide - ENSMUSP00000116523
Ensembl peptide - ENSMUSP00000123662
Ensembl peptide - ENSMUSP00000021614
Ensembl peptide - ENSMUSP00000114439
Ensembl peptide - ENSMUSP00000115313
NCBI entrez gene - 56421     See in Manteia.
MGI - MGI:1891833
RefSeq - XM_006516487
RefSeq - NM_001291071
RefSeq - NM_019703
RefSeq Peptide - NP_062677
RefSeq Peptide - NP_001278000
swissprot - A0A0G2JD99
swissprot - Q8C605
swissprot - F6VP95
swissprot - D3YUA3
swissprot - F6YL81
swissprot - Q9WUA3
Ensembl - ENSMUSG00000021196
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pfkpaENSDARG00000028000Danio rerio
 pfkpbENSDARG00000012801Danio rerio
 PFKPENSGALG00000006939Gallus gallus
 PFKPENSG00000067057Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pfkm / P47857 / Mus musculus phosphofructokinase, muscle (Pfkm), transcript variant 4, mRNA. / P08237* / phosphofructokinase, muscle*ENSMUSG0000003306565
Pfkl / P12382 / ATP-dependent 6-phosphofructokinase, liver type / P17858* / phosphofructokinase, liver type*ENSMUSG0000002027762


Protein motifs (from Interpro)
Interpro ID Name
 IPR000023  Phosphofructokinase domain
 IPR009161  ATP-dependent 6-phosphofructokinase, eukaryotic-type
 IPR015912  Phosphofructokinase, conserved site
 IPR022953  ATP-dependent 6-phosphofructokinase
 IPR035966  Phosphofructokinase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006002 fructose 6-phosphate metabolic process IEA
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0061615 glycolytic process through fructose-6-phosphate IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005945 6-phosphofructokinase complex ISS
 cellular_componentGO:0031012 extracellular matrix ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003872 6-phosphofructokinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020277 Pfkl / P12382 / ATP-dependent 6-phosphofructokinase, liver type / P17858* / phosphofructokinase, liver type*  / complex
 ENSMUSG00000021196 Pfkp / Q9WUA3 / ATP-dependent 6-phosphofructokinase, platelet type / Q01813* / phosphofructokinase, platelet*  / complex






 

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