ENSG00000069020


Homo sapiens

Features
Gene ID: ENSG00000069020
  
Biological name :MAST4
  
Synonyms : MAST4 / microtubule associated serine/threonine kinase family member 4 / O15021
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q12.3
Gene start: 66596361
Gene end: 67169595
  
Corresponding Affymetrix probe sets: 1554652_s_at (Human Genome U133 Plus 2.0 Array)   210958_s_at (Human Genome U133 Plus 2.0 Array)   222348_at (Human Genome U133 Plus 2.0 Array)   225611_at (Human Genome U133 Plus 2.0 Array)   225613_at (Human Genome U133 Plus 2.0 Array)   243575_at (Human Genome U133 Plus 2.0 Array)   40016_g_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398694
Ensembl peptide - ENSP00000400551
Ensembl peptide - ENSP00000421739
Ensembl peptide - ENSP00000413854
Ensembl peptide - ENSP00000413573
Ensembl peptide - ENSP00000407977
Ensembl peptide - ENSP00000404801
Ensembl peptide - ENSP00000261569
Ensembl peptide - ENSP00000384099
Ensembl peptide - ENSP00000384313
Ensembl peptide - ENSP00000384547
Ensembl peptide - ENSP00000385088
Ensembl peptide - ENSP00000385260
Ensembl peptide - ENSP00000385727
Ensembl peptide - ENSP00000392478
Ensembl peptide - ENSP00000396765
Ensembl peptide - ENSP00000398417
NCBI entrez gene - 375449     See in Manteia.
RefSeq - XM_017009453
RefSeq - NM_001164664
RefSeq - NM_001290226
RefSeq - NM_001290227
RefSeq - NM_001290228
RefSeq - NM_001297651
RefSeq - NM_015183
RefSeq - NM_198828
RefSeq - XM_006714606
RefSeq - XM_006714610
RefSeq - XM_011543382
RefSeq - XM_011543384
RefSeq - XM_011543385
RefSeq - XM_011543386
RefSeq - XM_017009447
RefSeq - XM_017009448
RefSeq - XM_017009449
RefSeq - XM_017009450
RefSeq - XM_017009451
RefSeq - XM_017009452
RefSeq Peptide - NP_001158136
RefSeq Peptide - NP_001277156
RefSeq Peptide - NP_001277157
RefSeq Peptide - NP_001284580
RefSeq Peptide - NP_055998
RefSeq Peptide - NP_942123
RefSeq Peptide - NP_001277155
swissprot - H7C0U3
swissprot - H7C146
swissprot - H7C1I9
swissprot - H7C2A9
swissprot - H7C2V7
swissprot - H7C3S4
swissprot - J3QT34
swissprot - B5MC73
swissprot - O15021
swissprot - E7EX28
swissprot - E7EWQ5
swissprot - D6RAK1
swissprot - C9JKM7
swissprot - C9J249
swissprot - F8WBH1
Ensembl - ENSG00000069020
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAST4ENSGALG00000014784Gallus gallus
 Mast4ENSMUSG00000034751Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAST2 / Q6P0Q8 / microtubule associated serine/threonine kinase 2ENSG0000008601539
MAST1 / Q9Y2H9 / microtubule associated serine/threonine kinase 1ENSG0000010561335
MAST3 / O60307 / microtubule associated serine/threonine kinase 3ENSG0000009930831
MASTL / Q96GX5 / microtubule associated serine/threonine kinase likeENSG000001205396


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001478  PDZ domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015022  Microtubule-associated serine/threonine-protein kinase, domain
 IPR023142  Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
 IPR028779  Microtubule-associated serine/threonine-protein kinase 2
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045075 regulation of interleukin-12 biosynthetic process IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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