ENSG00000105613


Homo sapiens

Features
Gene ID: ENSG00000105613
  
Biological name :MAST1
  
Synonyms : MAST1 / microtubule associated serine/threonine kinase 1 / Q9Y2H9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.13
Gene start: 12833951
Gene end: 12874951
  
Corresponding Affymetrix probe sets: 217231_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000251472
Ensembl peptide - ENSP00000465187
Ensembl peptide - ENSP00000465395
Ensembl peptide - ENSP00000466470
NCBI entrez gene - 22983     See in Manteia.
OMIM - 612256
RefSeq - XM_017026501
RefSeq - NM_014975
RefSeq - XM_011527805
RefSeq Peptide - NP_055790
swissprot - K7EJI7
swissprot - Q9Y2H9
swissprot - K7EJZ9
swissprot - K7EME4
Ensembl - ENSG00000105613
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mast1aENSDARG00000027497Danio rerio
 mast1bENSDARG00000088789Danio rerio
 Mast1ENSMUSG00000053693Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAST2 / Q6P0Q8 / microtubule associated serine/threonine kinase 2ENSG0000008601563
MAST4 / O15021 / microtubule associated serine/threonine kinase family member 4ENSG0000006902058
MAST3 / O60307 / microtubule associated serine/threonine kinase 3ENSG0000009930848
MASTL / Q96GX5 / microtubule associated serine/threonine kinase likeENSG0000012053910


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001478  PDZ domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015022  Microtubule-associated serine/threonine-protein kinase, domain
 IPR023142  Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
 IPR028777  Microtubule-associated serine/threonine-protein kinase 1
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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