ENSG00000069248


Homo sapiens

Features
Gene ID: ENSG00000069248
  
Biological name :NUP133
  
Synonyms : nucleoporin 133 / NUP133 / Q8WUM0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.13
Gene start: 229440260
Gene end: 229508341
  
Corresponding Affymetrix probe sets: 202184_s_at (Human Genome U133 Plus 2.0 Array)   233421_s_at (Human Genome U133 Plus 2.0 Array)   236905_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261396
NCBI entrez gene - 55746     See in Manteia.
OMIM - 607613
RefSeq - NM_018230
RefSeq Peptide - NP_060700
swissprot - Q8WUM0
Ensembl - ENSG00000069248
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup133ENSDARG00000010078Danio rerio
 NUP133ENSGALG00000011091Gallus gallus
 Nup133ENSMUSG00000039509Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007187  Nucleoporin, Nup133/Nup155-like, C-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery IBA
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006325 chromatin organization IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0006999 nuclear pore organization IMP
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0022008 neurogenesis IEA
 biological_processGO:0031081 nuclear pore distribution IBA
 biological_processGO:0048339 paraxial mesoderm development IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0061053 somite development IEA
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0000940 condensed chromosome outer kinetochore IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031080 nuclear pore outer ring NAS
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017056 structural constituent of nuclear pore IDA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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