ENSG00000070540


Homo sapiens

Features
Gene ID: ENSG00000070540
  
Biological name :WIPI1
  
Synonyms : Q5MNZ9 / WD repeat domain, phosphoinositide interacting 1 / WIPI1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q24.2
Gene start: 68420948
Gene end: 68457513
  
Corresponding Affymetrix probe sets: 203827_at (Human Genome U133 Plus 2.0 Array)   213836_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466270
Ensembl peptide - ENSP00000465557
Ensembl peptide - ENSP00000465695
Ensembl peptide - ENSP00000262139
Ensembl peptide - ENSP00000437345
Ensembl peptide - ENSP00000465470
NCBI entrez gene - 55062     See in Manteia.
OMIM - 609224
RefSeq - XM_017024808
RefSeq - NM_001320772
RefSeq - NM_017983
RefSeq Peptide - NP_001307701
RefSeq Peptide - NP_060453
swissprot - Q5MNZ9
swissprot - G5EA37
swissprot - K7EK57
swissprot - K7EKN0
swissprot - K7EKC5
swissprot - K7ELY0
Ensembl - ENSG00000070540
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wipi1ENSDARG00000040657Danio rerio
 WIPI1ENSGALG00000004215Gallus gallus
 Wipi1ENSMUSG00000041895Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WIPI2 / Q9Y4P8 / WD repeat domain, phosphoinositide interacting 2ENSG0000015795453


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR032909  WD repeat domain phosphoinositide-interacting protein 1
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006497 protein lipidation IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0034497 protein localization to phagophore assembly site IBA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0048203 vesicle targeting, trans-Golgi to endosome IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0000407 phagophore assembly site IDA
 cellular_componentGO:0000421 autophagosome membrane IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034045 phagophore assembly site membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030331 estrogen receptor binding IDA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0050681 androgen receptor binding IDA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
Macroautophagy
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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