ENSG00000070759


Homo sapiens

Features
Gene ID: ENSG00000070759
  
Biological name :TESK2
  
Synonyms : Q96S53 / TESK2 / testis-specific kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.1
Gene start: 45343883
Gene end: 45491166
  
Corresponding Affymetrix probe sets: 205486_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361156
Ensembl peptide - ENSP00000361158
NCBI entrez gene - 10420     See in Manteia.
OMIM - 604746
RefSeq - XM_017000049
RefSeq - NM_001320800
RefSeq - NM_007170
RefSeq - XM_011540500
RefSeq - XM_017000047
RefSeq - XM_017000048
RefSeq - XM_005270355
RefSeq - XM_006710287
RefSeq - XM_011540497
RefSeq Peptide - NP_009101
RefSeq Peptide - NP_001307729
swissprot - Q96S53
Ensembl - ENSG00000070759
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tesk2ENSDARG00000061450Danio rerio
 TESK2ENSGALG00000010230Gallus gallus
 Tesk2ENSMUSG00000033985Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TESK1 / Q15569 / testis-specific kinase 1ENSG0000010714048
LIMK1 / P53667 / LIM domain kinase 1ENSG0000010668324
LIMK2 / P53671 / LIM domain kinase 2ENSG0000018254122


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0048041 focal adhesion assembly IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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