ENSG00000107140


Homo sapiens

Features
Gene ID: ENSG00000107140
  
Biological name :TESK1
  
Synonyms : Q15569 / TESK1 / testis-specific kinase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p13.3
Gene start: 35605305
Gene end: 35610041
  
Corresponding Affymetrix probe sets: 204106_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000338127
Ensembl peptide - ENSP00000481045
NCBI entrez gene - 7016     See in Manteia.
OMIM - 601782
RefSeq - NM_001318230
RefSeq - NM_006285
RefSeq Peptide - NP_001305159
RefSeq Peptide - NP_006276
swissprot - Q15569
Ensembl - ENSG00000107140
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-113e8.3ENSDARG00000078251Danio rerio
 si:dkeyp-75h12.2ENSDARG00000079281Danio rerio
 TESK1ENSGALG00000027658Gallus gallus
 Tesk1ENSMUSG00000028458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TESK2 / Q96S53 / testis-specific kinase 2ENSG0000007075944
LIMK1 / P53667 / LIM domain kinase 1ENSG0000010668322
LIMK2 / P53671 / LIM domain kinase 2ENSG0000018254121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015782  Dual specificity testis-specific protein kinase 1
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0031953 negative regulation of protein autophosphorylation ISS
 biological_processGO:0032880 regulation of protein localization ISS
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0051496 positive regulation of stress fiber assembly TAS
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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