ENSG00000071894


Homo sapiens

Features
Gene ID: ENSG00000071894
  
Biological name :CPSF1
  
Synonyms : cleavage and polyadenylation specific factor 1 / CPSF1 / Q10570
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 144393229
Gene end: 144409349
  
Corresponding Affymetrix probe sets: 201638_s_at (Human Genome U133 Plus 2.0 Array)   201639_s_at (Human Genome U133 Plus 2.0 Array)   33132_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435761
Ensembl peptide - ENSP00000484669
Ensembl peptide - ENSP00000483775
Ensembl peptide - ENSP00000478161
Ensembl peptide - ENSP00000478145
NCBI entrez gene - 29894     See in Manteia.
OMIM - 606027
RefSeq - XM_011516997
RefSeq - XM_011516998
RefSeq - XM_011516999
RefSeq - NM_013291
RefSeq - XM_006716548
RefSeq - XM_006716549
RefSeq Peptide - NP_037423
swissprot - Q10570
swissprot - A0A087X101
swissprot - A0A087WTV4
swissprot - E9PIM1
Ensembl - ENSG00000071894
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpsf1ENSDARG00000034178Danio rerio
 Cpsf1ENSMUSG00000034022Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004871  Cleavage/polyadenylation specificity factor, A subunit, C-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006378 mRNA polyadenylation IMP
 biological_processGO:0006379 mRNA cleavage IBA
 biological_processGO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0098789 pre-mRNA cleavage required for polyadenylation IC
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding IDA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA Derived from an Intronless Transcript
tRNA processing in the nucleus
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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