ENSG00000072609


Homo sapiens

Features
Gene ID: ENSG00000072609
  
Biological name :CHFR
  
Synonyms : checkpoint with forkhead and ring finger domains / CHFR / Q96EP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.33
Gene start: 132822187
Gene end: 132956304
  
Corresponding Affymetrix probe sets: 1561940_at (Human Genome U133 Plus 2.0 Array)   218803_at (Human Genome U133 Plus 2.0 Array)   223931_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443761
Ensembl peptide - ENSP00000483699
Ensembl peptide - ENSP00000478791
Ensembl peptide - ENSP00000475247
Ensembl peptide - ENSP00000445371
Ensembl peptide - ENSP00000266880
Ensembl peptide - ENSP00000320557
Ensembl peptide - ENSP00000392395
Ensembl peptide - ENSP00000398735
Ensembl peptide - ENSP00000416431
Ensembl peptide - ENSP00000441837
Ensembl peptide - ENSP00000443237
NCBI entrez gene - 55743     See in Manteia.
OMIM - 605209
RefSeq - NM_018223
RefSeq - NM_001161347
RefSeq - NM_001161344
RefSeq - NM_001161345
RefSeq - NM_001161346
RefSeq Peptide - NP_060693
RefSeq Peptide - NP_001154816
RefSeq Peptide - NP_001154817
RefSeq Peptide - NP_001154818
RefSeq Peptide - NP_001154819
swissprot - U3KPU9
swissprot - A0A087X0W6
swissprot - A0A087WUN4
swissprot - F5GWH4
swissprot - F5H375
swissprot - F5H5P5
swissprot - F5H829
swissprot - Q96EP1
swissprot - A0A096P6K8
Ensembl - ENSG00000072609
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chfrENSDARG00000075347Danio rerio
 CHFRENSGALG00000002180Gallus gallus
 ChfrENSMUSG00000014668Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR001841  Zinc finger, RING-type
 IPR008984  SMAD/FHA domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007093 mitotic cell cycle checkpoint TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019941 modification-dependent protein catabolic process IDA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0000166 nucleotide binding IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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