ENSG00000074211


Homo sapiens

Features
Gene ID: ENSG00000074211
  
Biological name :PPP2R2C
  
Synonyms : PPP2R2C / protein phosphatase 2 regulatory subunit Bgamma / Q9Y2T4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.1
Gene start: 6320578
Gene end: 6563600
  
Corresponding Affymetrix probe sets: 223573_s_at (Human Genome U133 Plus 2.0 Array)   223574_x_at (Human Genome U133 Plus 2.0 Array)   228010_at (Human Genome U133 Plus 2.0 Array)   228025_s_at (Human Genome U133 Plus 2.0 Array)   228137_s_at (Human Genome U133 Plus 2.0 Array)   228140_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423650
Ensembl peptide - ENSP00000423649
Ensembl peptide - ENSP00000425247
Ensembl peptide - ENSP00000335083
Ensembl peptide - ENSP00000372042
Ensembl peptide - ENSP00000422374
NCBI entrez gene - 5522     See in Manteia.
OMIM - 605997
RefSeq - XM_011513496
RefSeq - NM_001206994
RefSeq - NM_001206995
RefSeq - NM_001206996
RefSeq - NM_020416
RefSeq - NM_181876
RefSeq - XM_011513495
RefSeq Peptide - NP_870991
RefSeq Peptide - NP_001193925
RefSeq Peptide - NP_065149
RefSeq Peptide - NP_001193924
RefSeq Peptide - NP_001193923
swissprot - D6R943
swissprot - Q9Y2T4
Ensembl - ENSG00000074211
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r2caENSDARG00000056797Danio rerio
 ppp2r2cbENSDARG00000062277Danio rerio
 PPP2R2CENSGALG00000015531Gallus gallus
 Q8BG02ENSMUSG00000029120Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q00005 / PPP2R2B / protein phosphatase 2 regulatory subunit BbetaENSG0000015647582
Q66LE6 / PPP2R2D / protein phosphatase 2 regulatory subunit BdeltaENSG0000017547080
P63151 / PPP2R2A / protein phosphatase 2 regulatory subunit BalphaENSG0000022191479


Protein motifs (from Interpro)
Interpro ID Name
 IPR000009  Protein phosphatase 2A regulatory subunit PR55
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR018067  Protein phosphatase 2A regulatory subunit PR55, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IBA
 biological_processGO:0032502 developmental process IBA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0070262 peptidyl-serine dephosphorylation IBA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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