ENSG00000175470


Homo sapiens

Features
Gene ID: ENSG00000175470
  
Biological name :PPP2R2D
  
Synonyms : PPP2R2D / protein phosphatase 2 regulatory subunit Bdelta / Q66LE6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.3
Gene start: 131900644
Gene end: 131959834
  
Corresponding Affymetrix probe sets: 221772_s_at (Human Genome U133 Plus 2.0 Array)   225066_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481133
Ensembl peptide - ENSP00000485636
Ensembl peptide - ENSP00000399970
Ensembl peptide - ENSP00000428418
NCBI entrez gene - 55844     See in Manteia.
OMIM - 613992
RefSeq - XM_017016408
RefSeq - NM_001291310
RefSeq - NM_018461
RefSeq - XM_006717914
RefSeq - XM_006717915
RefSeq Peptide - NP_001278239
RefSeq Peptide - NP_060931
swissprot - A0A0A6YYD6
swissprot - H0YB06
swissprot - Q66LE6
swissprot - A0A096LPI9
Ensembl - ENSG00000175470
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6NY64ENSDARG00000102009Danio rerio
 PPP2R2DENSGALG00000010471Gallus gallus
 Q925E7ENSMUSG00000041769Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P63151 / PPP2R2A / protein phosphatase 2 regulatory subunit BalphaENSG0000022191486
Q00005 / PPP2R2B / protein phosphatase 2 regulatory subunit BbetaENSG0000015647582
Q9Y2T4 / PPP2R2C / protein phosphatase 2 regulatory subunit BgammaENSG0000007421179


Protein motifs (from Interpro)
Interpro ID Name
 IPR000009  Protein phosphatase 2A regulatory subunit PR55
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR018067  Protein phosphatase 2A regulatory subunit PR55, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010458 exit from mitosis ISS
 biological_processGO:0032502 developmental process IBA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070262 peptidyl-serine dephosphorylation IBA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
MASTL Facilitates Mitotic Progression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000128989 ARPP19 / P56211 / cAMP regulated phosphoprotein 19  / reaction / complex
 ENSG00000143420 ENSA / O43768 / endosulfine alpha  / complex / reaction






 

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