ENSG00000143420


Homo sapiens

Features
Gene ID: ENSG00000143420
  
Biological name :ENSA
  
Synonyms : endosulfine alpha / ENSA / O43768
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 150600851
Gene end: 150629612
  
Corresponding Affymetrix probe sets: 202596_at (Human Genome U133 Plus 2.0 Array)   221486_at (Human Genome U133 Plus 2.0 Array)   221487_s_at (Human Genome U133 Plus 2.0 Array)   228851_s_at (Human Genome U133 Plus 2.0 Array)   228852_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424242
Ensembl peptide - ENSP00000422343
Ensembl peptide - ENSP00000426110
Ensembl peptide - ENSP00000492428
Ensembl peptide - ENSP00000271690
Ensembl peptide - ENSP00000341743
Ensembl peptide - ENSP00000348921
Ensembl peptide - ENSP00000354835
Ensembl peptide - ENSP00000355220
Ensembl peptide - ENSP00000355239
Ensembl peptide - ENSP00000358010
Ensembl peptide - ENSP00000358012
Ensembl peptide - ENSP00000421458
NCBI entrez gene - 2029     See in Manteia.
OMIM - 603061
RefSeq - NM_004436
RefSeq - NM_207042
RefSeq - NM_207043
RefSeq - NM_207044
RefSeq - NM_207045
RefSeq - NM_207046
RefSeq - NM_207047
RefSeq - NM_207168
RefSeq Peptide - NP_996928
RefSeq Peptide - NP_996929
RefSeq Peptide - NP_996930
RefSeq Peptide - NP_997051
RefSeq Peptide - NP_996926
RefSeq Peptide - NP_004427
RefSeq Peptide - NP_996925
RefSeq Peptide - NP_996927
swissprot - A0A1W2PRU0
swissprot - Q5T5H1
swissprot - A6NMQ3
swissprot - O43768
Ensembl - ENSG00000143420
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ensaaENSDARG00000036944Danio rerio
 ensabENSDARG00000061644Danio rerio
 Q5ZIF8ENSGALG00000037480Gallus gallus
 EnsaENSMUSG00000038619Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARPP19 / P56211 / cAMP regulated phosphoprotein 19ENSG0000012898961


Protein motifs (from Interpro)
Interpro ID Name
 IPR006760  Endosulphine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle ISS
 biological_processGO:0000278 mitotic cell cycle ISS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007584 response to nutrient TAS
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0035308 negative regulation of protein dephosphorylation IBA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0050796 regulation of insulin secretion IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IBA
 molecular_functionGO:0005102 signaling receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008200 ion channel inhibitor activity TAS
 molecular_functionGO:0019212 phosphatase inhibitor activity ISS
 molecular_functionGO:0019870 potassium channel inhibitor activity IDA
 molecular_functionGO:0019888 protein phosphatase regulator activity ISS
 molecular_functionGO:0051721 protein phosphatase 2A binding ISS


Pathways (from Reactome)
Pathway description
MASTL Facilitates Mitotic Progression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175470 Q66LE6 / PPP2R2D / protein phosphatase 2 regulatory subunit Bdelta  / complex / reaction
 ENSG00000120539 MASTL / Q96GX5 / microtubule associated serine/threonine kinase like  / reaction






 

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