ENSG00000128989


Homo sapiens

Features
Gene ID: ENSG00000128989
  
Biological name :ARPP19
  
Synonyms : ARPP19 / cAMP regulated phosphoprotein 19 / P56211
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.2
Gene start: 52547045
Gene end: 52569883
  
Corresponding Affymetrix probe sets: 214553_s_at (Human Genome U133 Plus 2.0 Array)   221482_s_at (Human Genome U133 Plus 2.0 Array)   221483_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457631
Ensembl peptide - ENSP00000457123
Ensembl peptide - ENSP00000457805
Ensembl peptide - ENSP00000249822
Ensembl peptide - ENSP00000454234
Ensembl peptide - ENSP00000454297
Ensembl peptide - ENSP00000454341
Ensembl peptide - ENSP00000454612
Ensembl peptide - ENSP00000455151
Ensembl peptide - ENSP00000455610
Ensembl peptide - ENSP00000455625
Ensembl peptide - ENSP00000455986
NCBI entrez gene - 10776     See in Manteia.
OMIM - 605487
RefSeq - XM_017021871
RefSeq - NM_001306191
RefSeq - NM_001306195
RefSeq - NM_001306196
RefSeq - NM_001330309
RefSeq - NM_006628
RefSeq - XM_017021868
RefSeq - XM_017021869
RefSeq - XM_017021870
RefSeq Peptide - NP_001293120
RefSeq Peptide - NP_001293124
RefSeq Peptide - NP_001293125
RefSeq Peptide - NP_001317238
RefSeq Peptide - NP_006619
swissprot - A0A024R5U3
swissprot - P56211
swissprot - H3BMD8
swissprot - H3BQ52
swissprot - H3BTD3
Ensembl - ENSG00000128989
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arpp19aENSDARG00000032532Danio rerio
 arpp19bENSDARG00000039880Danio rerio
 ARPP19ENSGALG00000017370Gallus gallus
 Arpp19ENSMUSG00000007656Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSA / O43768 / endosulfine alphaENSG0000014342063


Protein motifs (from Interpro)
Interpro ID Name
 IPR006760  Endosulphine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IMP
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007212 dopamine receptor signaling pathway IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0035308 negative regulation of protein dephosphorylation IBA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0045722 positive regulation of gluconeogenesis IDA
 biological_processGO:0046326 positive regulation of glucose import NAS
 biological_processGO:0046579 positive regulation of Ras protein signal transduction IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0005102 signaling receptor binding IDA
 molecular_functionGO:0015459 potassium channel regulator activity IDA
 molecular_functionGO:0019212 phosphatase inhibitor activity ISS
 molecular_functionGO:0019888 protein phosphatase regulator activity ISS
 molecular_functionGO:0051721 protein phosphatase 2A binding ISS


Pathways (from Reactome)
Pathway description
MASTL Facilitates Mitotic Progression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175470 Q66LE6 / PPP2R2D / protein phosphatase 2 regulatory subunit Bdelta  / reaction / complex
 ENSG00000120539 MASTL / Q96GX5 / microtubule associated serine/threonine kinase like  / reaction






 

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