ENSG00000077616


Homo sapiens

Features
Gene ID: ENSG00000077616
  
Biological name :NAALAD2
  
Synonyms : NAALAD2 / N-acetylated alpha-linked acidic dipeptidase 2 / Q9Y3Q0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q14.3
Gene start: 90131515
Gene end: 90192894
  
Corresponding Affymetrix probe sets: 1554504_at (Human Genome U133 Plus 2.0 Array)   1554506_x_at (Human Genome U133 Plus 2.0 Array)   1554507_at (Human Genome U133 Plus 2.0 Array)   222161_at (Human Genome U133 Plus 2.0 Array)   233815_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365111
Ensembl peptide - ENSP00000435670
Ensembl peptide - ENSP00000435249
Ensembl peptide - ENSP00000433710
Ensembl peptide - ENSP00000432481
Ensembl peptide - ENSP00000431989
Ensembl peptide - ENSP00000320083
NCBI entrez gene - 10003     See in Manteia.
OMIM - 611636
RefSeq - XM_017017046
RefSeq - NM_001300930
RefSeq - NM_005467
RefSeq - XM_017017043
RefSeq - XM_017017044
RefSeq - XM_017017045
RefSeq Peptide - NP_005458
RefSeq Peptide - NP_001287859
swissprot - E9PII2
swissprot - E9PJV2
swissprot - J3KNJ3
swissprot - E9PKX5
swissprot - Q9Y3Q0
swissprot - E9PJ53
Ensembl - ENSG00000077616
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 naalad2ENSDARG00000021383Danio rerio
 Q9CZR2ENSMUSG00000043943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOLH1 / Q04609 / folate hydrolase 1ENSG0000008620569
Q9UQQ1 / NAALADL1 / N-acetylated alpha-linked acidic dipeptidase like 1ENSG0000016806038
TFRC / P02786 / transferrin receptorENSG0000007227425
TFR2 / Q9UP52 / transferrin receptor 2ENSG0000010632725
Q58DX5 / NAALADL2 / N-acetylated alpha-linked acidic dipeptidase like 2ENSG0000017769423


Protein motifs (from Interpro)
Interpro ID Name
 IPR003137  PA domain
 IPR007365  Transferrin receptor-like, dimerisation domain
 IPR007484  Peptidase M28
 IPR036757  Transferrin receptor-like, dimerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis NAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process TAS
 biological_processGO:0042135 neurotransmitter catabolic process IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004180 carboxypeptidase activity NAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity NAS
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008239 dipeptidyl-peptidase activity NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016805 dipeptidase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050129 N-formylglutamate deformylase activity IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000077616 Q9Y3Q0 / NAALAD2 / N-acetylated alpha-linked acidic dipeptidase 2  / complex






 

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