ENSG00000077800


Homo sapiens

Features
Gene ID: ENSG00000077800
  
Biological name :FKBP6
  
Synonyms : FK506 binding protein 6 / FKBP6 / O75344
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q11.23
Gene start: 73328164
Gene end: 73358637
  
Corresponding Affymetrix probe sets: 206763_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415891
Ensembl peptide - ENSP00000403908
Ensembl peptide - ENSP00000416277
Ensembl peptide - ENSP00000252037
Ensembl peptide - ENSP00000394952
Ensembl peptide - ENSP00000402360
NCBI entrez gene - 8468     See in Manteia.
OMIM - 604839
RefSeq - XM_017012742
RefSeq - NM_001135211
RefSeq - NM_001281304
RefSeq - NM_003602
RefSeq - XM_006716153
RefSeq - XM_017012741
RefSeq Peptide - NP_003593
RefSeq Peptide - NP_001268233
RefSeq Peptide - NP_001128683
swissprot - C9JM01
swissprot - F8WD38
swissprot - F8WD36
swissprot - O75344
Ensembl - ENSG00000077800
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fkbp6ENSDARG00000030133Danio rerio
 FKBP6ENSGALG00000029211Gallus gallus
 Fkbp6ENSMUSG00000040013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FKBP8 / Q14318 / FK506 binding protein 8ENSG0000010570124


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0007283 spermatogenesis ISS
 biological_processGO:0018208 peptidyl-proline modification IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031047 gene silencing by RNA ISS
 biological_processGO:0034587 piRNA metabolic process IEA
 biological_processGO:0043046 DNA methylation involved in gamete generation IEA
 biological_processGO:0045070 positive regulation of viral genome replication IMP
 biological_processGO:0051321 meiotic cell cycle ISS
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 cellular_componentGO:0000795 synaptonemal complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005528 FK506 binding TAS
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051879 Hsp90 protein binding IEA


Pathways (from Reactome)
Pathway description
Meiotic synapsis
PIWI-interacting RNA (piRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000080824 P07900 / HSP90AA1 / heat shock protein 90 alpha family class A member 1  / complex






 

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