ENSG00000105701


Homo sapiens

Features
Gene ID: ENSG00000105701
  
Biological name :FKBP8
  
Synonyms : FK506 binding protein 8 / FKBP8 / Q14318
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 18531751
Gene end: 18544077
  
Corresponding Affymetrix probe sets: 208255_s_at (Human Genome U133 Plus 2.0 Array)   222007_s_at (Human Genome U133 Plus 2.0 Array)   40850_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475588
Ensembl peptide - ENSP00000477278
Ensembl peptide - ENSP00000476767
Ensembl peptide - ENSP00000475895
Ensembl peptide - ENSP00000222308
Ensembl peptide - ENSP00000441267
Ensembl peptide - ENSP00000471700
Ensembl peptide - ENSP00000472043
Ensembl peptide - ENSP00000472087
Ensembl peptide - ENSP00000472302
Ensembl peptide - ENSP00000472643
Ensembl peptide - ENSP00000472731
Ensembl peptide - ENSP00000472921
NCBI entrez gene - 23770     See in Manteia.
OMIM - 604840
RefSeq - XM_011527864
RefSeq - NM_001308373
RefSeq - NM_012181
RefSeq - XM_011527863
RefSeq Peptide - NP_001295302
RefSeq Peptide - NP_036313
swissprot - M0R304
swissprot - V9GZ05
swissprot - A0A0A0MTJ1
swissprot - Q14318
swissprot - U3KQ64
swissprot - U3KQI1
swissprot - A0A024R7P2
swissprot - M0R1Q0
swissprot - M0R2K9
swissprot - M0R1S6
swissprot - M0R2Q6
Ensembl - ENSG00000105701
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fkbp8ENSDARG00000001734Danio rerio
 FKBP8ENSGALG00000003357Gallus gallus
 Fkbp8ENSMUSG00000019428Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FKBP6 / O75344 / FK506 binding protein 6ENSG0000007780019


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR001440  Tetratricopeptide repeat 1
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013105  Tetratricopeptide repeat 2
 IPR019734  Tetratricopeptide repeat
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0001708 cell fate specification IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0021904 dorsal/ventral neural tube patterning IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0030510 regulation of BMP signaling pathway IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005740 mitochondrial envelope IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0032991 protein-containing complex IMP
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005528 FK506 binding IBA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IPI


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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