ENSG00000078699


Homo sapiens

Features
Gene ID: ENSG00000078699
  
Biological name :CBFA2T2
  
Synonyms : CBFA2/RUNX1 translocation partner 2 / CBFA2T2 / O43439
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.21
Gene start: 33490075
Gene end: 33650036
  
Corresponding Affymetrix probe sets: 1554637_a_at (Human Genome U133 Plus 2.0 Array)   207625_s_at (Human Genome U133 Plus 2.0 Array)   209144_s_at (Human Genome U133 Plus 2.0 Array)   209145_s_at (Human Genome U133 Plus 2.0 Array)   233243_at (Human Genome U133 Plus 2.0 Array)   238549_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443398
Ensembl peptide - ENSP00000262653
Ensembl peptide - ENSP00000341865
Ensembl peptide - ENSP00000380902
Ensembl peptide - ENSP00000433270
Ensembl peptide - ENSP00000345810
Ensembl peptide - ENSP00000352622
Ensembl peptide - ENSP00000364428
NCBI entrez gene - 9139     See in Manteia.
OMIM - 603672
RefSeq - XM_017028125
RefSeq - NM_001032999
RefSeq - NM_001039709
RefSeq - NM_005093
RefSeq - XM_011529107
RefSeq - XM_017028121
RefSeq - XM_017028122
RefSeq - XM_017028123
RefSeq - XM_017028124
RefSeq - XM_011529101
RefSeq - XM_011529102
RefSeq - XM_011529103
RefSeq Peptide - NP_001034798
RefSeq Peptide - NP_005084
RefSeq Peptide - NP_001028171
swissprot - O43439
swissprot - Q68DC6
Ensembl - ENSG00000078699
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbfa2t2ENSDARG00000074337Danio rerio
 CBFA2T2ENSGALG00000003096Gallus gallus
 O70374ENSMUSG00000038533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q06455 / RUNX1T1 / RUNX1 translocation partner 1ENSG0000007910262
O75081 / CBFA2T3 / CBFA2/RUNX1 translocation partner 3ENSG0000012999358
DEAF1 / O75398 / DEAF1, transcription factorENSG0000017703013


Protein motifs (from Interpro)
Interpro ID Name
 IPR002893  Zinc finger, MYND-type
 IPR003894  TAFH/NHR1
 IPR013289  CBFA2T family
 IPR013291  Myeloid transforming gene-related protein-1 (MTGR1)
 IPR014896  NHR2-like
 IPR037249  TAFH/NHR1 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010976 positive regulation of neuron projection development IDA
 biological_processGO:0010977 negative regulation of neuron projection development ISS
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0060575 intestinal epithelial cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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