ENSG00000129993


Homo sapiens

Features
Gene ID: ENSG00000129993
  
Biological name :CBFA2T3
  
Synonyms : CBFA2/RUNX1 translocation partner 3 / CBFA2T3 / O75081
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q24.3
Gene start: 88874858
Gene end: 88977204
  
Corresponding Affymetrix probe sets: 208056_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464125
Ensembl peptide - ENSP00000456717
Ensembl peptide - ENSP00000457410
Ensembl peptide - ENSP00000268679
Ensembl peptide - ENSP00000332122
Ensembl peptide - ENSP00000454609
Ensembl peptide - ENSP00000454851
Ensembl peptide - ENSP00000454872
Ensembl peptide - ENSP00000456102
NCBI entrez gene - 863     See in Manteia.
OMIM - 603870
RefSeq - XM_017023811
RefSeq - NM_005187
RefSeq - NM_175931
RefSeq - XM_005256323
RefSeq - XM_011523419
RefSeq Peptide - NP_005178
RefSeq Peptide - NP_787127
swissprot - O75081
swissprot - H3BMZ0
swissprot - H3BNH2
swissprot - H3BNI7
swissprot - H3BR72
swissprot - H3BU07
swissprot - H3BSI4
swissprot - J3QRB1
Ensembl - ENSG00000129993
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbfa2t3ENSDARG00000079012Danio rerio
 CBFA2T3ENSGALG00000032410Gallus gallus
 O54972ENSMUSG00000006362Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q06455 / RUNX1T1 / RUNX1 translocation partner 1ENSG0000007910267
O43439 / CBFA2T2 / CBFA2/RUNX1 translocation partner 2ENSG0000007869954
DEAF1 / O75398 / DEAF1, transcription factorENSG0000017703015


Protein motifs (from Interpro)
Interpro ID Name
 IPR002893  Zinc finger, MYND-type
 IPR003894  TAFH/NHR1
 IPR013289  CBFA2T family
 IPR013292  Protein CBFA2T3
 IPR014896  NHR2-like
 IPR037249  TAFH/NHR1 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030851 granulocyte differentiation IDA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0045820 negative regulation of glycolytic process IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:1903715 regulation of aerobic respiration IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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