ENSG00000084110


Homo sapiens

Features
Gene ID: ENSG00000084110
  
Biological name :HAL
  
Synonyms : HAL / histidine ammonia-lyase / P42357
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q23.1
Gene start: 95972662
Gene end: 95996365
  
Corresponding Affymetrix probe sets: 206643_at (Human Genome U133 Plus 2.0 Array)   217521_at (Human Genome U133 Plus 2.0 Array)   237967_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450372
Ensembl peptide - ENSP00000447543
Ensembl peptide - ENSP00000447675
Ensembl peptide - ENSP00000261208
Ensembl peptide - ENSP00000439385
Ensembl peptide - ENSP00000440861
Ensembl peptide - ENSP00000446364
Ensembl peptide - ENSP00000446678
NCBI entrez gene - 3034     See in Manteia.
OMIM - 609457
RefSeq - XM_017019246
RefSeq - NM_001258333
RefSeq - NM_001258334
RefSeq - NM_002108
RefSeq - XM_011538249
RefSeq Peptide - NP_001245263
RefSeq Peptide - NP_002099
RefSeq Peptide - NP_001245262
swissprot - P42357
swissprot - F8VNX0
swissprot - Q4VB95
swissprot - F8W0V1
swissprot - H0YHB0
Ensembl - ENSG00000084110
  
Related genetic diseases (OMIM): 235800 - [Histidinemia], 235800
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 halENSDARG00000017444Danio rerio
 HALENSGALG00000011421Gallus gallus
 HalENSMUSG00000020017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001106  Aromatic amino acid lyase
 IPR005921  Histidine ammonia-lyase
 IPR008948  L-Aspartase-like
 IPR021922  Par3/HAL, N-terminal
 IPR022313  Phenylalanine/histidine ammonia-lyases, active site
 IPR024083  Fumarase/histidase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006547 histidine metabolic process IEA
 biological_processGO:0006548 histidine catabolic process TAS
 biological_processGO:0019556 histidine catabolic process to glutamate and formamide IEA
 biological_processGO:0019557 histidine catabolic process to glutamate and formate IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004397 histidine ammonia-lyase activity EXP
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016841 ammonia-lyase activity IEA


Pathways (from Reactome)
Pathway description
Histidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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