ENSMUSG00000020017


Mus musculus

Features
Gene ID: ENSMUSG00000020017
  
Biological name :Hal
  
Synonyms : Hal / Histidine ammonia-lyase / P35492
  
Possible biological names infered from orthology : P42357
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C2
Gene start: 93488768
Gene end: 93519304
  
Corresponding Affymetrix probe sets: 10365769 (MoGene1.0st)   1418645_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123336
Ensembl peptide - ENSMUSP00000016031
NCBI entrez gene - 15109     See in Manteia.
MGI - MGI:96010
RefSeq - NM_010401
RefSeq Peptide - NP_034531
swissprot - P35492
swissprot - B2RXW1
swissprot - F8WH73
Ensembl - ENSMUSG00000020017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 halENSDARG00000017444Danio rerio
 HALENSGALG00000011421Gallus gallus
 HALENSG00000084110Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001106  Aromatic amino acid lyase
 IPR005921  Histidine ammonia-lyase
 IPR008948  L-Aspartase-like
 IPR021922  Par3/HAL, N-terminal
 IPR022313  Phenylalanine/histidine ammonia-lyases, active site
 IPR024083  Fumarase/histidase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006547 histidine metabolic process IEA
 biological_processGO:0006548 histidine catabolic process IDA
 biological_processGO:0019556 histidine catabolic process to glutamate and formamide IEA
 biological_processGO:0019557 histidine catabolic process to glutamate and formate IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004397 histidine ammonia-lyase activity ISO
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016841 ammonia-lyase activity IEA


Pathways (from Reactome)
Pathway description
Histidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011654 increased urine histidine level "increased excretion of histidine and related imidazole metabolites in urine" [MGI:llw2]
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Allelic Composition: Cisd2Gt(XS0445)Wtsi/Cisd2Gt(XS0445)Wtsi
Genetic Background: B6.129P2-Cisd2Gt(XS0445)Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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