ENSG00000084623


Homo sapiens

Features
Gene ID: ENSG00000084623
  
Biological name :EIF3I
  
Synonyms : EIF3I / eukaryotic translation initiation factor 3 subunit I / Q13347
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.2
Gene start: 32221928
Gene end: 32231604
  
Corresponding Affymetrix probe sets: 208756_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000347194
Ensembl peptide - ENSP00000362688
NCBI entrez gene - 8668     See in Manteia.
OMIM - 603911
RefSeq - XM_017002671
RefSeq - NM_003757
RefSeq Peptide - NP_003748
swissprot - Q13347
swissprot - Q5TFK1
swissprot - Q5U0F4
Ensembl - ENSG00000084623
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3iENSDARG00000017445Danio rerio
 EIF3IENSGALG00000003337Gallus gallus
 Eif3iENSMUSG00000028798Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STRAP / Q9Y3F4 / serine/threonine kinase receptor associated proteinENSG0000002373425


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR027525  Eukaryotic translation initiation factor 3 subunit I
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IEA
 molecular_functionGO:0003743 translation initiation factor activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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