ENSG00000086102


Homo sapiens

Features
Gene ID: ENSG00000086102
  
Biological name :NFX1
  
Synonyms : NFX1 / nuclear transcription factor, X-box binding 1 / Q12986
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p13.3
Gene start: 33290511
Gene end: 33371157
  
Corresponding Affymetrix probe sets: 1553103_at (Human Genome U133 Plus 2.0 Array)   1553348_a_at (Human Genome U133 Plus 2.0 Array)   202584_at (Human Genome U133 Plus 2.0 Array)   202585_s_at (Human Genome U133 Plus 2.0 Array)   210268_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317695
Ensembl peptide - ENSP00000368856
NCBI entrez gene - 4799     See in Manteia.
OMIM - 603255
RefSeq - NM_002504
RefSeq - NM_001318758
RefSeq - NM_147134
RefSeq Peptide - NP_001305687
RefSeq Peptide - NP_002495
RefSeq Peptide - NP_667345
swissprot - Q12986
Ensembl - ENSG00000086102
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-10f23.2ENSDARG00000105669Danio rerio
 NFX1ENSGALG00000043724Gallus gallus
 Nfx1ENSMUSG00000028423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFXL1 / Q6ZNB6 / nuclear transcription factor, X-box binding like 1ENSG0000017044820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000967  Zinc finger, NF-X1-type
 IPR001374  R3H domain
 IPR001841  Zinc finger, RING-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034076  Transcriptional repressor NF-X1, R3H domain
 IPR034078  Transcription factor NFX1 family
 IPR036867  R3H domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0045347 negative regulation of MHC class II biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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