ENSG00000170448


Homo sapiens

Features
Gene ID: ENSG00000170448
  
Biological name :NFXL1
  
Synonyms : NFXL1 / nuclear transcription factor, X-box binding like 1 / Q6ZNB6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p12
Gene start: 47847233
Gene end: 47914667
  
Corresponding Affymetrix probe sets: 227220_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333113
Ensembl peptide - ENSP00000370949
Ensembl peptide - ENSP00000422037
Ensembl peptide - ENSP00000425812
NCBI entrez gene - 152518     See in Manteia.
RefSeq - NM_001278624
RefSeq - NM_001278623
RefSeq - NM_152995
RefSeq Peptide - NP_001265552
RefSeq Peptide - NP_001265553
RefSeq Peptide - NP_694540
swissprot - Q6ZNB6
Ensembl - ENSG00000170448
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfxl1ENSDARG00000070127Danio rerio
 NFXL1ENSGALG00000014138Gallus gallus
 Nfxl1ENSMUSG00000072889Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFX1 / Q12986 / nuclear transcription factor, X-box binding 1ENSG0000008610225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000967  Zinc finger, NF-X1-type
 IPR001841  Zinc finger, RING-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR034078  Transcription factor NFX1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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