ENSMUSG00000072889


Mus musculus

Features
Gene ID: ENSMUSG00000072889
  
Biological name :Nfxl1
  
Synonyms : Nfxl1 / nuclear transcription factor, X-box binding like 1
  
Possible biological names infered from orthology : Q6ZNB6
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: C3.2
Gene start: 72513301
Gene end: 72559684
  
Corresponding Affymetrix probe sets: 10530467 (MoGene1.0st)   10530477 (MoGene1.0st)   10530492 (MoGene1.0st)   1417145_at (Mouse Genome 430 2.0 Array)   1430365_at (Mouse Genome 430 2.0 Array)   1457208_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074481
Ensembl peptide - ENSMUSP00000114355
Ensembl peptide - ENSMUSP00000084467
NCBI entrez gene - 100978     See in Manteia.
MGI - MGI:1923646
RefSeq - NM_133921
RefSeq - XM_011240686
RefSeq Peptide - NP_598682
swissprot - E9Q3K1
swissprot - E9PZN0
swissprot - E9Q8I7
Ensembl - ENSMUSG00000072889
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfxl1ENSDARG00000070127Danio rerio
 NFXL1ENSGALG00000014138Gallus gallus
 NFXL1ENSG00000170448Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nfx1 / B1AY10 / Transcriptional repressor NF-X1 / Q12986* / nuclear transcription factor, X-box binding 1*ENSMUSG0000002842325


Protein motifs (from Interpro)
Interpro ID Name
 IPR000967  Zinc finger, NF-X1-type
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR034078  Transcription factor NFX1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Myoz1tm1a(EUCOMM)Hmgu/Myoz1tm1a(EUCOMM)Hmgu
Genetic Background: Not Specified

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Myoz1tm1a(EUCOMM)Hmgu/Myoz1tm1a(EUCOMM)Hmgu
Genetic Background: Not Specified

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myoz1tm1a(EUCOMM)Hmgu/Myoz1tm1a(EUCOMM)Hmgu
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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