ENSMUSG00000028423


Mus musculus

Features
Gene ID: ENSMUSG00000028423
  
Biological name :Nfx1
  
Synonyms : B1AY10 / Nfx1 / Transcriptional repressor NF-X1
  
Possible biological names infered from orthology : nuclear transcription factor, X-box binding 1 / Q12986
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 40970906
Gene end: 41025993
  
Corresponding Affymetrix probe sets: 10504017 (MoGene1.0st)   1419752_at (Mouse Genome 430 2.0 Array)   1419753_at (Mouse Genome 430 2.0 Array)   1428248_at (Mouse Genome 430 2.0 Array)   1442397_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030133
Ensembl peptide - ENSMUSP00000089203
Ensembl peptide - ENSMUSP00000095747
NCBI entrez gene - 74164     See in Manteia.
MGI - MGI:1921414
RefSeq - XM_011250124
RefSeq - NM_001290448
RefSeq - NM_001290449
RefSeq - NM_023739
RefSeq - XM_006538319
RefSeq - XM_011250123
RefSeq Peptide - NP_076228
RefSeq Peptide - NP_001277377
RefSeq Peptide - NP_001277378
swissprot - B1AY10
Ensembl - ENSMUSG00000028423
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-10f23.2ENSDARG00000105669Danio rerio
 NFX1ENSGALG00000043724Gallus gallus
 NFX1ENSG00000086102Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nfxl1 / nuclear transcription factor, X-box binding like 1 / Q6ZNB6*ENSMUSG0000007288920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000967  Zinc finger, NF-X1-type
 IPR001374  R3H domain
 IPR001841  Zinc finger, RING-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR034076  Transcriptional repressor NF-X1, R3H domain
 IPR034078  Transcription factor NFX1 family
 IPR036867  R3H domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045347 negative regulation of MHC class II biosynthetic process IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr