ENSG00000086619


Homo sapiens

Features
Gene ID: ENSG00000086619
  
Biological name :ERO1B
  
Synonyms : endoplasmic reticulum oxidoreductase 1 beta / ERO1B / Q86YB8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.3
Gene start: 236215555
Gene end: 236281985
  
Corresponding Affymetrix probe sets: 220012_at (Human Genome U133 Plus 2.0 Array)   231944_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264181
Ensembl peptide - ENSP00000346635
Ensembl peptide - ENSP00000355548
NCBI entrez gene - 56605     See in Manteia.
OMIM - 615437
RefSeq - NM_019891
RefSeq Peptide - NP_063944
swissprot - Q5T1H5
swissprot - Q5TAE8
swissprot - Q86YB8
Ensembl - ENSG00000086619
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ero1bENSDARG00000103915Danio rerio
 ERO1BENSGALG00000040000Gallus gallus
 Ero1lbENSMUSG00000057069Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERO1A / Q96HE7 / endoplasmic reticulum oxidoreductase 1 alphaENSG0000019793060


Protein motifs (from Interpro)
Interpro ID Name
 IPR007266  Endoplasmic reticulum oxidoreductin 1
 IPR037192  ERO1-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0006464 cellular protein modification process IBA
 biological_processGO:0019471 4-hydroxyproline metabolic process IEA
 biological_processGO:0022417 protein maturation by protein folding IEA
 biological_processGO:0030070 insulin processing IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0034975 protein folding in endoplasmic reticulum IBA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003756 protein disulfide isomerase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity NAS
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
 molecular_functionGO:0051082 unfolded protein binding NAS


Pathways (from Reactome)
Pathway description
Insulin processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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