ENSG00000087253


Homo sapiens

Features
Gene ID: ENSG00000087253
  
Biological name :LPCAT2
  
Synonyms : LPCAT2 / lysophosphatidylcholine acyltransferase 2 / Q7L5N7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q12.2
Gene start: 55508998
Gene end: 55586670
  
Corresponding Affymetrix probe sets: 222833_at (Human Genome U133 Plus 2.0 Array)   227889_at (Human Genome U133 Plus 2.0 Array)   229791_at (Human Genome U133 Plus 2.0 Array)   239598_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262134
Ensembl peptide - ENSP00000457496
NCBI entrez gene - 54947     See in Manteia.
OMIM - 612040
RefSeq - XM_017023376
RefSeq - NM_017839
RefSeq - XM_005256006
RefSeq - XM_011523169
RefSeq Peptide - NP_060309
swissprot - H3BU68
swissprot - Q7L5N7
Ensembl - ENSG00000087253
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lpcat2ENSDARG00000053010Danio rerio
 LPCAT2ENSGALG00000003574Gallus gallus
 Lpcat2ENSMUSG00000033192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPCAT1 / Q8NF37 / lysophosphatidylcholine acyltransferase 1ENSG0000015339541
LPCAT4 / Q643R3 / lysophosphatidylcholine acyltransferase 4ENSG0000017645438


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR002123  Phospholipid/glycerol acyltransferase
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0006663 platelet activating factor biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0036151 phosphatidylcholine acyl-chain remodeling IDA
 biological_processGO:0061024 membrane organization IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity TAS
 molecular_functionGO:0047184 1-acylglycerophosphocholine O-acyltransferase activity ISS
 molecular_functionGO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity ISS


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr