ENSG00000088387


Homo sapiens

Features
Gene ID: ENSG00000088387
  
Biological name :DOCK9
  
Synonyms : dedicator of cytokinesis 9 / DOCK9 / Q9BZ29
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q32.3
Gene start: 98793429
Gene end: 99086625
  
Corresponding Affymetrix probe sets: 212538_at (Human Genome U133 Plus 2.0 Array)   215041_s_at (Human Genome U133 Plus 2.0 Array)   215237_at (Human Genome U133 Plus 2.0 Array)   215238_s_at (Human Genome U133 Plus 2.0 Array)   232874_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406883
Ensembl peptide - ENSP00000403528
Ensembl peptide - ENSP00000407610
Ensembl peptide - ENSP00000490569
Ensembl peptide - ENSP00000487551
Ensembl peptide - ENSP00000486606
Ensembl peptide - ENSP00000486269
Ensembl peptide - ENSP00000413781
Ensembl peptide - ENSP00000341086
Ensembl peptide - ENSP00000344702
Ensembl peptide - ENSP00000365643
Ensembl peptide - ENSP00000383087
Ensembl peptide - ENSP00000388193
Ensembl peptide - ENSP00000396897
Ensembl peptide - ENSP00000401958
NCBI entrez gene - 23348     See in Manteia.
OMIM - 607325
RefSeq - XM_017020521
RefSeq - XM_006719937
RefSeq - XM_017020503
RefSeq - XM_017020504
RefSeq - XM_017020505
RefSeq - XM_017020506
RefSeq - XM_017020507
RefSeq - XM_017020508
RefSeq - XM_017020509
RefSeq - XM_017020510
RefSeq - XM_017020511
RefSeq - XM_017020512
RefSeq - XM_017020513
RefSeq - XM_017020514
RefSeq - XM_017020515
RefSeq - XM_017020516
RefSeq - XM_017020517
RefSeq - XM_017020518
RefSeq - XM_017020519
RefSeq - XM_017020520
RefSeq - NM_001130048
RefSeq - NM_001130049
RefSeq - NM_001130050
RefSeq - NM_001318849
RefSeq - NM_015296
RefSeq - XM_005254034
RefSeq - XM_005254035
RefSeq - XM_006719922
RefSeq - XM_006719924
RefSeq - XM_006719925
RefSeq - XM_006719931
RefSeq - XM_006719932
RefSeq - XM_006719936
RefSeq Peptide - NP_001123521
RefSeq Peptide - NP_001123522
RefSeq Peptide - NP_001305778
RefSeq Peptide - NP_056111
RefSeq Peptide - NP_001123520
swissprot - H0Y3S1
swissprot - H0Y572
swissprot - H7BZ79
swissprot - Q5JUD8
swissprot - Q6ZSL5
swissprot - Q9BZ29
swissprot - X6RGR3
swissprot - A0A088AWN3
swissprot - A0A1B0GVL8
swissprot - Q5JUD3
swissprot - A0A0D9SFH5
swissprot - A0A0D9SF41
swissprot - A0A0A0MT38
swissprot - A0A0A0MSY4
Ensembl - ENSG00000088387
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DOCK9 (1 of many)ENSDARG00000114086Danio rerio
 dock9bENSDARG00000016311Danio rerio
 DOCK9ENSGALG00000016883Gallus gallus
 Dock9ENSMUSG00000025558Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DOCK11 / Q5JSL3 / dedicator of cytokinesis 11ENSG0000014725159
DOCK10 / Q96BY6 / dedicator of cytokinesis 10ENSG0000013590554
DOCK8 / Q8NF50 / dedicator of cytokinesis 8ENSG0000010709929
DOCK6 / Q96HP0 / dedicator of cytokinesis 6ENSG0000013015829
DOCK7 / Q96N67 / dedicator of cytokinesis 7ENSG0000011664129


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR010703  Dedicator of cytokinesis, C-terminal
 IPR011989  Armadillo-like helical
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR011993  PH-like domain superfamily
 IPR016024  Armadillo-type fold
 IPR021816  Dedicator of cytokinesis C/D, N-terminal
 IPR026791  Dedicator of cytokinesis
 IPR026796  Dedicator of cytokinesis 9
 IPR027007  DHR-1 domain
 IPR027357  DHR-2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0008150 biological_process ND
 biological_processGO:0043547 positive regulation of GTPase activity ISS
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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