ENSG00000088827


Homo sapiens

Features
Gene ID: ENSG00000088827
  
Biological name :SIGLEC1
  
Synonyms : Q9BZZ2 / sialic acid binding Ig like lectin 1 / SIGLEC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 3686970
Gene end: 3707128
  
Corresponding Affymetrix probe sets: 219519_s_at (Human Genome U133 Plus 2.0 Array)   44673_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000341141
Ensembl peptide - ENSP00000395778
NCBI entrez gene - 6614     See in Manteia.
OMIM - 600751
RefSeq - XM_011529332
RefSeq - NM_023068
RefSeq - XM_011529329
RefSeq - XM_011529330
RefSeq - XM_011529331
RefSeq - XM_006723610
RefSeq - XM_011529324
RefSeq - XM_011529325
RefSeq - XM_011529326
RefSeq - XM_011529327
RefSeq - XM_011529328
RefSeq Peptide - NP_075556
swissprot - Q9BZZ2
swissprot - H7C0M6
Ensembl - ENSG00000088827
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Siglec1ENSMUSG00000027322Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD22 / P20273 / CD22 moleculeENSG0000001212412
VCAM1 / P19320 / vascular cell adhesion molecule 1ENSG000001626928


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006954 inflammatory response NAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion NAS
 biological_processGO:0098609 cell-cell adhesion NAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0030246 carbohydrate binding NAS


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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