ENSG00000012124


Homo sapiens

Features
Gene ID: ENSG00000012124
  
Biological name :CD22
  
Synonyms : CD22 / CD22 molecule / P20273
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35319261
Gene end: 35347355
  
Corresponding Affymetrix probe sets: 204581_at (Human Genome U133 Plus 2.0 Array)   217422_s_at (Human Genome U133 Plus 2.0 Array)   220674_at (Human Genome U133 Plus 2.0 Array)   38521_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473221
Ensembl peptide - ENSP00000472762
Ensembl peptide - ENSP00000482823
Ensembl peptide - ENSP00000085219
Ensembl peptide - ENSP00000339349
Ensembl peptide - ENSP00000403822
Ensembl peptide - ENSP00000441237
Ensembl peptide - ENSP00000442279
Ensembl peptide - ENSP00000469503
Ensembl peptide - ENSP00000469523
Ensembl peptide - ENSP00000469980
Ensembl peptide - ENSP00000469984
Ensembl peptide - ENSP00000470193
Ensembl peptide - ENSP00000470681
Ensembl peptide - ENSP00000470724
Ensembl peptide - ENSP00000471399
Ensembl peptide - ENSP00000471972
Ensembl peptide - ENSP00000472664
NCBI entrez gene - 933     See in Manteia.
OMIM - 107266
RefSeq - NM_001185100
RefSeq - NM_001771
RefSeq - NM_001278417
RefSeq - NM_001185101
RefSeq - NM_001185099
RefSeq Peptide - NP_001172029
RefSeq Peptide - NP_001172028
RefSeq Peptide - NP_001172030
RefSeq Peptide - NP_001265346
RefSeq Peptide - NP_001762
swissprot - M0R2R8
swissprot - M0R3H1
swissprot - M0QZP5
swissprot - M0QZ01
swissprot - M0QYP4
swissprot - M0QY14
swissprot - M0QY05
swissprot - P20273
swissprot - A0A087WZQ4
swissprot - Q0EAF5
swissprot - M0QZR7
swissprot - M0R0R6
swissprot - M0R1M2
swissprot - M0R2M0
Ensembl - ENSG00000012124
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BX927068.2ENSDARG00000096621Danio rerio
 cd22ENSDARG00000053005Danio rerio
 si:ch211-152f2.1ENSDARG00000092322Danio rerio
 si:ch211-152f2.2ENSDARG00000034910Danio rerio
 si:ch211-152f2.3ENSDARG00000043445Danio rerio
 si:ch211-152f2.4ENSDARG00000096574Danio rerio
 si:ch211-1f22.10ENSDARG00000096619Danio rerio
 si:ch211-1f22.11ENSDARG00000094524Danio rerio
 si:ch211-1f22.12ENSDARG00000093845Danio rerio
 si:ch211-1f22.13ENSDARG00000096623Danio rerio
 si:ch211-1f22.14ENSDARG00000062309Danio rerio
 si:ch211-1f22.16ENSDARG00000096670Danio rerio
 si:ch211-1f22.3ENSDARG00000101532Danio rerio
 si:ch211-1f22.5ENSDARG00000054655Danio rerio
 si:ch211-1f22.6ENSDARG00000096656Danio rerio
 si:ch211-1f22.7ENSDARG00000096543Danio rerio
 si:ch211-1f22.8ENSDARG00000096507Danio rerio
 si:ch211-1f22.9ENSDARG00000096585Danio rerio
 si:ch73-94k4.1ENSDARG00000096634Danio rerio
 si:ch73-94k4.3ENSDARG00000096671Danio rerio
 si:ch73-94k4.5ENSDARG00000096523Danio rerio
 si:dkey-24p1.1ENSDARG00000039096Danio rerio
 si:dkey-27j5.10ENSDARG00000094157Danio rerio
 si:dkey-27j5.11ENSDARG00000096650Danio rerio
 si:dkey-27j5.6ENSDARG00000086301Danio rerio
 si:dkey-27j5.7ENSDARG00000096570Danio rerio
 si:dkey-27j5.8ENSDARG00000096534Danio rerio
 si:dkey-33i11.1ENSDARG00000053027Danio rerio
 zgc:171470ENSDARG00000057844Danio rerio
 zmp:0000001289ENSDARG00000089894Danio rerio
 Cd22ENSMUSG00000030577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BZZ2 / SIGLEC1 / sialic acid binding Ig like lectin 1ENSG0000008882724
VCAM1 / P19320 / vascular cell adhesion molecule 1ENSG0000016269215


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013162  CD80-like, immunoglobulin C2-set
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
CD22 mediated BCR regulation
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000012124 CD22 / P20273 / CD22 molecule  / reaction / -
 ENSG00000211899 IGHM / P01871 / immunoglobulin heavy constant mu  / reaction / complex
 ENSG00000105369 CD79A / P11912 / CD79a molecule  / complex / reaction
 ENSG00000007312 CD79B / P40259 / CD79b molecule  / reaction / complex
 ENSG00000211898 IGHD / P01880 / immunoglobulin heavy constant delta  / reaction / complex
 ENSG00000111679 PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6  / reaction / complex
 ENSG00000254087 LYN / P07948 / LYN proto-oncogene, Src family tyrosine kinase  / reaction






 

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