ENSG00000089723


Homo sapiens

Features
Gene ID: ENSG00000089723
  
Biological name :OTUB2
  
Synonyms : OTUB2 / OTU deubiquitinase, ubiquitin aldehyde binding 2 / Q96DC9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.12
Gene start: 94026329
Gene end: 94048930
  
Corresponding Affymetrix probe sets: 1555682_at (Human Genome U133 Plus 2.0 Array)   219369_s_at (Human Genome U133 Plus 2.0 Array)   222878_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000203664
Ensembl peptide - ENSP00000451283
NCBI entrez gene - 78990     See in Manteia.
OMIM - 608338
RefSeq - XM_011537148
RefSeq - NM_023112
RefSeq - XM_005268055
RefSeq Peptide - NP_075601
swissprot - Q96DC9
Ensembl - ENSG00000089723
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Otub2ENSMUSG00000021203Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OTUB1 / Q96FW1 / OTU deubiquitinase, ubiquitin aldehyde binding 1ENSG0000016777045


Protein motifs (from Interpro)
Interpro ID Name
 IPR003323  OTU domain
 IPR016615  Ubiquitin thioesterase Otubain
 IPR019400  Peptidase C65, otubain
 IPR030299  Ubiquitin thioesterase OTUB2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016579 protein deubiquitination IMP
 biological_processGO:0035871 protein K11-linked deubiquitination IDA
 biological_processGO:0070536 protein K63-linked deubiquitination IDA
 biological_processGO:0071108 protein K48-linked deubiquitination IDA
 cellular_componentGO:0005634 nucleus HDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019784 NEDD8-specific protease activity IBA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0043130 ubiquitin binding IBA


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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