ENSMUSG00000021203


Mus musculus

Features
Gene ID: ENSMUSG00000021203
  
Biological name :Otub2
  
Synonyms : Otub2 / Q9CQX0 / Ubiquitin thioesterase OTUB2
  
Possible biological names infered from orthology : OTU deubiquitinase, ubiquitin aldehyde binding 2 / Q96DC9
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: E
Gene start: 103388682
Gene end: 103406350
  
Corresponding Affymetrix probe sets: 10397966 (MoGene1.0st)   1417575_at (Mouse Genome 430 2.0 Array)   1417576_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137162
Ensembl peptide - ENSMUSP00000021620
Ensembl peptide - ENSMUSP00000098655
Ensembl peptide - ENSMUSP00000115673
NCBI entrez gene - 68149     See in Manteia.
MGI - MGI:1915399
RefSeq - NM_026580
RefSeq - XM_006516185
RefSeq - NM_001177841
RefSeq Peptide - NP_001171312
RefSeq Peptide - NP_080856
swissprot - D3Z0Y8
swissprot - Q9CQX0
swissprot - F6SXD2
Ensembl - ENSMUSG00000021203
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OTUB2ENSG00000089723Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Otub1 / Q7TQI3 / Ubiquitin thioesterase OTUB1 / Q96FW1* / OTU deubiquitinase, ubiquitin aldehyde binding 1*ENSMUSG0000002476733


Protein motifs (from Interpro)
Interpro ID Name
 IPR003323  OTU domain
 IPR016615  Ubiquitin thioesterase Otubain
 IPR019400  Peptidase C65, otubain
 IPR030299  Ubiquitin thioesterase OTUB2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0035871 protein K11-linked deubiquitination IBA
 biological_processGO:0070536 protein K63-linked deubiquitination ISO
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019784 NEDD8-specific protease activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0043130 ubiquitin binding IEA


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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