ENSG00000090273


Homo sapiens

Features
Gene ID: ENSG00000090273
  
Biological name :NUDC
  
Synonyms : nuclear distribution C, dynein complex regulator / NUDC / Q9Y266
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.11
Gene start: 26900238
Gene end: 26946862
  
Corresponding Affymetrix probe sets: 201173_x_at (Human Genome U133 Plus 2.0 Array)   210574_s_at (Human Genome U133 Plus 2.0 Array)   210575_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000400981
Ensembl peptide - ENSP00000404020
Ensembl peptide - ENSP00000319664
NCBI entrez gene - 10726     See in Manteia.
OMIM - 610325
RefSeq - XM_017000096
RefSeq - XM_011540529
RefSeq - XM_011540530
RefSeq - XM_017000094
RefSeq - XM_017000095
RefSeq - NM_006600
RefSeq Peptide - NP_006591
swissprot - A0A0A0MSU9
swissprot - A0A0A0MSS4
swissprot - Q9Y266
Ensembl - ENSG00000090273
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudcENSDARG00000104837Danio rerio
 NUDCENSGALG00000000895Gallus gallus
 NudcENSMUSG00000028851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NUDCD3 / Q8IVD9 / NudC domain containing 3ENSG0000001567627


Protein motifs (from Interpro)
Interpro ID Name
 IPR007052  CS domain
 IPR008978  HSP20-like chaperone
 IPR025934  NudC N-terminal domain
 IPR032572  Nuclear migration protein nudC


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051082 unfolded protein binding IBA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
Mitotic Telophase/Cytokinesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000166851 PLK1 / P53350 / polo like kinase 1  / reaction






 

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