ENSG00000095739


Homo sapiens

Features
Gene ID: ENSG00000095739
  
Biological name :BAMBI
  
Synonyms : BAMBI / BMP and activin membrane bound inhibitor / Q13145
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p12.1
Gene start: 28677342
Gene end: 28682939
  
Corresponding Affymetrix probe sets: 203304_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364683
NCBI entrez gene - 25805     See in Manteia.
OMIM - 604444
RefSeq - NM_012342
RefSeq Peptide - NP_036474
swissprot - Q13145
Ensembl - ENSG00000095739
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bambiaENSDARG00000055381Danio rerio
 bambibENSDARG00000099677Danio rerio
 BAMBIENSGALG00000040993Gallus gallus
 BambiENSMUSG00000024232Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009345  BMP and activin membrane-bound inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008360 regulation of cell shape IMP
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0016477 cell migration IDA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0032092 positive regulation of protein binding IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005109 frizzled binding IPI
 molecular_functionGO:0005114 type II transforming growth factor beta receptor binding TAS


Pathways (from Reactome)
Pathway description
Downregulation of TGF-beta receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101665 SMAD7 / O15105 / SMAD family member 7  / reaction / complex
 ENSG00000105329 TGFB1 / P01137 / transforming growth factor beta 1  / reaction / complex
 ENSG00000163513 P37173 / TGFBR2 / transforming growth factor beta receptor 2  / complex / reaction
 ENSG00000106799 P36897 / TGFBR1 / transforming growth factor beta receptor 1  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr