Manteia

ENSG00000095794

Homo sapiens

Features

Gene ID:	ENSG00000095794

Biological name :	CREM

Synonyms :	cAMP responsive element modulator / CREM / Q03060

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	10
Strand:	1
Band:	p11.21
Gene start:	35126791
Gene end:	35212958

Corresponding Affymetrix probe sets:	207630_s_at (Human Genome U133 Plus 2.0 Array) 209967_s_at (Human Genome U133 Plus 2.0 Array) 210171_s_at (Human Genome U133 Plus 2.0 Array) 214508_x_at (Human Genome U133 Plus 2.0 Array) 228092_at (Human Genome U133 Plus 2.0 Array) 230511_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000419684 Ensembl peptide - ENSP00000419075 Ensembl peptide - ENSP00000419810 Ensembl peptide - ENSP00000473519 Ensembl peptide - ENSP00000420681 Ensembl peptide - ENSP00000420511 Ensembl peptide - ENSP00000420453 Ensembl peptide - ENSP00000420437 Ensembl peptide - ENSP00000419924 Ensembl peptide - ENSP00000265372 Ensembl peptide - ENSP00000337138 Ensembl peptide - ENSP00000341875 Ensembl peptide - ENSP00000344365 Ensembl peptide - ENSP00000345384 Ensembl peptide - ENSP00000346804 Ensembl peptide - ENSP00000349387 Ensembl peptide - ENSP00000354593 Ensembl peptide - ENSP00000363853 Ensembl peptide - ENSP00000363858 Ensembl peptide - ENSP00000363860 Ensembl peptide - ENSP00000363866 Ensembl peptide - ENSP00000379225 Ensembl peptide - ENSP00000393538 Ensembl peptide - ENSP00000403938 Ensembl peptide - ENSP00000409220 Ensembl peptide - ENSP00000417058 Ensembl peptide - ENSP00000417130 Ensembl peptide - ENSP00000417165 Ensembl peptide - ENSP00000417327 Ensembl peptide - ENSP00000417399 Ensembl peptide - ENSP00000417460 Ensembl peptide - ENSP00000417562 Ensembl peptide - ENSP00000417807 Ensembl peptide - ENSP00000418336 Ensembl peptide - ENSP00000418450 Ensembl peptide - ENSP00000418798 Ensembl peptide - ENSP00000419018 NCBI entrez gene - 1390 See in Manteia. OMIM - 123812 RefSeq - XM_017015737 RefSeq - NM_182769 RefSeq - NM_182770 RefSeq - NM_182771 RefSeq - NM_182772 RefSeq - NM_183011 RefSeq - NM_183012 RefSeq - NM_183013 RefSeq - NM_183060 RefSeq - XM_006717378 RefSeq - XM_006717379 RefSeq - XM_006717382 RefSeq - XM_006717383 RefSeq - XM_006717387 RefSeq - XM_011519316 RefSeq - XM_011519324 RefSeq - XM_011519325 RefSeq - XM_011519327 RefSeq - XM_011519330 RefSeq - XM_011519331 RefSeq - XM_011519332 RefSeq - XM_011519333 RefSeq - XM_011519335 RefSeq - XM_017015716 RefSeq - XM_017015717 RefSeq - XM_017015718 RefSeq - XM_017015719 RefSeq - XM_017015720 RefSeq - XM_017015721 RefSeq - XM_017015722 RefSeq - XM_017015723 RefSeq - XM_017015724 RefSeq - XM_017015725 RefSeq - XM_017015726 RefSeq - XM_017015727 RefSeq - XM_017015728 RefSeq - XM_017015729 RefSeq - XM_017015730 RefSeq - XM_017015731 RefSeq - XM_017015733 RefSeq - XM_017015734 RefSeq - XM_017015735 RefSeq - XM_017015736 RefSeq - NM_001267562 RefSeq - NM_001267563 RefSeq - NM_001267564 RefSeq - NM_001267567 RefSeq - NM_001267570 RefSeq - NM_001881 RefSeq - NM_181571 RefSeq - NM_182717 RefSeq - NM_182718 RefSeq - NM_182719 RefSeq - NM_182720 RefSeq - NM_182721 RefSeq - NM_182723 RefSeq - NM_182724 RefSeq Peptide - NP_001339394 RefSeq Peptide - NP_877570 RefSeq Peptide - NP_877571 RefSeq Peptide - NP_877572 RefSeq Peptide - NP_877573 RefSeq Peptide - NP_898829 RefSeq Peptide - NP_898830 RefSeq Peptide - NP_898831 RefSeq Peptide - NP_898883 RefSeq Peptide - NP_001254491 RefSeq Peptide - NP_001254492 RefSeq Peptide - NP_001254493 RefSeq Peptide - NP_001254496 RefSeq Peptide - NP_001254499 RefSeq Peptide - NP_001339374 RefSeq Peptide - NP_001339375 RefSeq Peptide - NP_001339395 RefSeq Peptide - NP_001339396 RefSeq Peptide - NP_001872 RefSeq Peptide - NP_853549 RefSeq Peptide - NP_874386 RefSeq Peptide - NP_874387 RefSeq Peptide - NP_874388 RefSeq Peptide - NP_874389 RefSeq Peptide - NP_874390 RefSeq Peptide - NP_874392 RefSeq Peptide - NP_874393 swissprot - E9PAR2 swissprot - C9K092 swissprot - C9J5A7 swissprot - C9J2J0 swissprot - C9IYM9 swissprot - F8WB03 swissprot - F8WDF2 swissprot - G5E998 swissprot - H7C4X0 swissprot - J3KQC0 swissprot - J3KR46 swissprot - R4GN75 swissprot - A0A0A0MSU8 swissprot - E9PB41 swissprot - Q03060 Ensembl - ENSG00000095794

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
crema	ENSDARG00000023217	Danio rerio
CREM	ENSGALG00000007082	Gallus gallus
Crem	ENSMUSG00000063889	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
CREB1 / P16220 / cAMP responsive element binding protein 1	ENSG00000118260	58
ATF1 / P18846 / activating transcription factor 1	ENSG00000123268	45

Protein motifs (from Interpro)

Interpro ID	Name
IPR001630	cAMP response element binding (CREB) protein
IPR003102	Coactivator CBP, pKID
IPR004827	Basic-leucine zipper domain
IPR008917	Transcription factor, Skn-1-like, DNA-binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP
biological_process	GO:0006006	glucose metabolic process	IEA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	NAS
biological_process	GO:0006631	fatty acid metabolic process	IEA
biological_process	GO:0006687	glycosphingolipid metabolic process	IEA
biological_process	GO:0007165	signal transduction	TAS
biological_process	GO:0007275	multicellular organism development	IEA
biological_process	GO:0007283	spermatogenesis	IEA
biological_process	GO:0030154	cell differentiation	IEA
biological_process	GO:0042752	regulation of circadian rhythm	IEA
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II	IEA
biological_process	GO:0048384	retinoic acid receptor signaling pathway	IEA
biological_process	GO:0048511	rhythmic process	IEA
cellular_component	GO:0005634	nucleus	TAS
cellular_component	GO:0005667	transcription factor complex	IEA
cellular_component	GO:0005737	cytoplasm	IEA
molecular_function	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	IDA
molecular_function	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	NAS
molecular_function	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding	IC
molecular_function	GO:0003677	DNA binding	NAS
molecular_function	GO:0003700	DNA-binding transcription factor activity	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0008140	cAMP response element binding protein binding	NAS

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr