ENSG00000123268


Homo sapiens

Features
Gene ID: ENSG00000123268
  
Biological name :ATF1
  
Synonyms : activating transcription factor 1 / ATF1 / P18846
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.12
Gene start: 50763710
Gene end: 50821122
  
Corresponding Affymetrix probe sets: 1558233_s_at (Human Genome U133 Plus 2.0 Array)   1565269_s_at (Human Genome U133 Plus 2.0 Array)   222103_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448421
Ensembl peptide - ENSP00000448921
Ensembl peptide - ENSP00000448987
Ensembl peptide - ENSP00000262053
Ensembl peptide - ENSP00000448592
NCBI entrez gene - 466     See in Manteia.
OMIM - 123803
RefSeq - XM_017019336
RefSeq - XM_011538388
RefSeq - XM_017019331
RefSeq - XM_017019332
RefSeq - XM_017019333
RefSeq - XM_017019334
RefSeq - XM_017019335
RefSeq - NM_005171
RefSeq - XM_011538386
RefSeq - XM_011538387
RefSeq Peptide - NP_005162
swissprot - F8VS03
swissprot - F8VYE5
swissprot - F8VYN3
swissprot - F8VRN2
swissprot - P18846
Ensembl - ENSG00000123268
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atf1ENSDARG00000044301Danio rerio
 ENSGALG00000033614Gallus gallus
 Atf1ENSMUSG00000023027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CREB1 / P16220 / cAMP responsive element binding protein 1ENSG0000011826062
CREM / Q03060 / cAMP responsive element modulatorENSG0000009579450


Protein motifs (from Interpro)
Interpro ID Name
 IPR001630  cAMP response element binding (CREB) protein
 IPR003102  Coactivator CBP, pKID
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029825  cAMP-dependent transcription factor ATF1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0032025 response to cobalt ion IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:1990590 ATF1-ATF4 transcription factor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
CREB phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100784 O75582 / RPS6KA5 / ribosomal protein S6 kinase A5  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr