ENSG00000100665


Homo sapiens

Features
Gene ID: ENSG00000100665
  
Biological name :SERPINA4
  
Synonyms : P29622 / SERPINA4 / serpin family A member 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.13
Gene start: 94561091
Gene end: 94569913
  
Corresponding Affymetrix probe sets: 213874_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451172
Ensembl peptide - ENSP00000298841
Ensembl peptide - ENSP00000450838
NCBI entrez gene - 5267     See in Manteia.
OMIM - 147935
RefSeq - NM_001289032
RefSeq - NM_001289033
RefSeq - NM_006215
RefSeq Peptide - NP_001275961
RefSeq Peptide - NP_001275962
RefSeq Peptide - NP_006206
swissprot - P29622
swissprot - A0A024R6I9
Ensembl - ENSG00000100665
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serpina1ENSDARG00000090286Danio rerio
 serpina1lENSDARG00000090850Danio rerio
 serpina7ENSDARG00000087143Danio rerio
 si:ch211-186e20.2ENSDARG00000074712Danio rerio
 si:ch211-186e20.7ENSDARG00000077960Danio rerio
 zgc:174259ENSDARG00000091136Danio rerio
 ENSGALG00000020390Gallus gallus
 ENSGALG00000020388Gallus gallus
 ENSGALG00000046409Gallus gallus
 ENSGALG00000028598Gallus gallus
 SPIA1ENSGALG00000023070Gallus gallus
 SPIA4ENSGALG00000010969Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86WD7 / SERPINA9 / serpin family A member 9ENSG0000017005445
P01011 / SERPINA3 / serpin family A member 3ENSG0000019613643
P05154 / SERPINA5 / serpin family A member 5ENSG0000018848843
P05543 / SERPINA7 / serpin family A member 7ENSG0000012356142
Q86U17 / SERPINA11 / serpin family A member 11ENSG0000018691042
P01009 / SERPINA1 / serpin family A member 1ENSG0000019724942
P08185 / SERPINA6 / serpin family A member 6ENSG0000017009941
Q8IW75 / SERPINA12 / serpin family A member 12ENSG0000016595331
P05546 / SERPIND1 / serpin family D member 1ENSG0000009993728
Q9UK55 / SERPINA10 / serpin family A member 10ENSG0000014009328
SERPINA2 / serpin family A member 2 (gene/pseudogene)ENSG0000025859725


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0031089 platelet dense granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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