ENSG00000100842


Homo sapiens

Features
Gene ID: ENSG00000100842
  
Biological name :EFS
  
Synonyms : EFS / embryonal Fyn-associated substrate / O43281
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q11.2
Gene start: 23356402
Gene end: 23365752
  
Corresponding Affymetrix probe sets: 204400_at (Human Genome U133 Plus 2.0 Array)   210880_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216733
Ensembl peptide - ENSP00000340607
Ensembl peptide - ENSP00000416684
NCBI entrez gene - 10278     See in Manteia.
OMIM - 609906
RefSeq - XM_005267256
RefSeq - NM_001277174
RefSeq - NM_005864
RefSeq - NM_032459
RefSeq Peptide - NP_005855
RefSeq Peptide - NP_115835
RefSeq Peptide - NP_001264103
swissprot - O43281
Ensembl - ENSG00000100842
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 efsENSDARG00000088835Danio rerio
 EfsENSMUSG00000022203Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCAR1 / P56945 / BCAR1, Cas family scaffolding proteinENSG0000005082037
NEDD9 / Q14511 / neural precursor cell expressed, developmentally down-regulated 9ENSG0000011185933
CASS4 / Q9NQ75 / Cas scaffolding protein family member 4ENSG0000008758921


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR021901  CAS family, C-terminal
 IPR035747  Embryonal Fyn-associated substrate, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR037362  CAS family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0035556 intracellular signal transduction TAS
 cellular_componentGO:0005737 cytoplasm TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019904 protein domain specific binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr