ENSG00000101405


Homo sapiens

Features
Gene ID: ENSG00000101405
  
Biological name :OXT
  
Synonyms : OXT / oxytocin/neurophysin I prepropeptide / P01178
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p13
Gene start: 3071620
Gene end: 3072517
  
Corresponding Affymetrix probe sets: 207576_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000217386
NCBI entrez gene - 5020     See in Manteia.
OMIM - 167050
RefSeq - XM_011529238
RefSeq - NM_000915
RefSeq Peptide - NP_000906
swissprot - P01178
swissprot - X5D7M6
Ensembl - ENSG00000101405
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 avpENSDARG00000058567Danio rerio
 oxtENSDARG00000042845Danio rerio
 ENSGALG00000019026Gallus gallus
 OxtENSMUSG00000027301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AVP / P01185 / arginine vasopressinENSG0000010120068


Protein motifs (from Interpro)
Interpro ID Name
 IPR000981  Neurohypophysial hormone
 IPR022423  Neurohypophysial hormone, conserved site
 IPR036387  Neurohypophysial hormone domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0002125 maternal aggressive behavior IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0009744 response to sucrose IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010701 positive regulation of norepinephrine secretion IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0030431 sleep IEA
 biological_processGO:0032094 response to food IEA
 biological_processGO:0032308 positive regulation of prostaglandin secretion IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0034695 response to prostaglandin E IEA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035811 negative regulation of urine volume IEA
 biological_processGO:0035815 positive regulation of renal sodium excretion IEA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042538 hyperosmotic salinity response IEA
 biological_processGO:0042711 maternal behavior IEA
 biological_processGO:0042713 sperm ejaculation IEA
 biological_processGO:0042755 eating behavior IEA
 biological_processGO:0042756 drinking behavior IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0044058 regulation of digestive system process IEA
 biological_processGO:0045472 response to ether IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0045778 positive regulation of ossification IEA
 biological_processGO:0045925 positive regulation of female receptivity IEA
 biological_processGO:0048545 response to steroid hormone IEA
 biological_processGO:0050806 positive regulation of synaptic transmission IEA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0051930 regulation of sensory perception of pain IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0060179 male mating behavior IEA
 biological_processGO:0060406 positive regulation of penile erection IEA
 biological_processGO:0060450 positive regulation of hindgut contraction IEA
 biological_processGO:0060455 negative regulation of gastric acid secretion IEA
 biological_processGO:0070474 positive regulation of uterine smooth muscle contraction IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0043195 terminal bouton IEA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IEA
 molecular_functionGO:0005185 neurohypophyseal hormone activity IEA
 molecular_functionGO:0031855 oxytocin receptor binding IEA


Pathways (from Reactome)
Pathway description
Vasopressin-like receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000180914 OXTR / P30559 / oxytocin receptor  / reaction / complex






 

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