ENSG00000101972


Homo sapiens

Features
Gene ID: ENSG00000101972
  
Biological name :STAG2
  
Synonyms : Q8N3U4 / STAG2 / stromal antigen 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q25
Gene start: 123960212
Gene end: 124422664
  
Corresponding Affymetrix probe sets: 207983_s_at (Human Genome U133 Plus 2.0 Array)   209022_at (Human Genome U133 Plus 2.0 Array)   209023_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360202
Ensembl peptide - ENSP00000360199
Ensembl peptide - ENSP00000377987
Ensembl peptide - ENSP00000415103
Ensembl peptide - ENSP00000405874
Ensembl peptide - ENSP00000405555
Ensembl peptide - ENSP00000401309
Ensembl peptide - ENSP00000397265
Ensembl peptide - ENSP00000392118
Ensembl peptide - ENSP00000377988
Ensembl peptide - ENSP00000218089
Ensembl peptide - ENSP00000360186
Ensembl peptide - ENSP00000360187
NCBI entrez gene - 10735     See in Manteia.
OMIM - 300826
RefSeq - XM_017029235
RefSeq - NM_001042751
RefSeq - NM_001282418
RefSeq - NM_006603
RefSeq - XM_005262357
RefSeq - XM_005262358
RefSeq - XM_005262359
RefSeq - XM_005262360
RefSeq - XM_005262361
RefSeq - XM_006724727
RefSeq - XM_006724728
RefSeq - XM_011531253
RefSeq - XM_017029232
RefSeq - XM_017029233
RefSeq - XM_017029234
RefSeq - NM_001042749
RefSeq - NM_001042750
RefSeq Peptide - NP_001036215
RefSeq Peptide - NP_001036216
RefSeq Peptide - NP_001269347
RefSeq Peptide - NP_006594
RefSeq Peptide - NP_001036214
swissprot - B1AMT0
swissprot - B1AMS9
swissprot - Q8N3U4
swissprot - B1AMS8
swissprot - E7ERE6
swissprot - B1AMT4
swissprot - B1AMT3
swissprot - B1AMT2
swissprot - B1AMT1
Ensembl - ENSG00000101972
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stag2aENSDARG00000011783Danio rerio
 stag2bENSDARG00000053668Danio rerio
 STAG2ENSGALG00000008482Gallus gallus
 Stag2ENSMUSG00000025862Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAG1 / Q8WVM7 / stromal antigen 1ENSG0000011800770
STAG3 / Q9UJ98 / stromal antigen 3ENSG0000006692347


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR013721  STAG
 IPR016024  Armadillo-type fold
 IPR020839  Stromalin conservative domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007062 sister chromatid cohesion IMP
 biological_processGO:0032876 negative regulation of DNA endoreduplication IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:1901673 regulation of mitotic spindle assembly IMP
 cellular_componentGO:0000775 chromosome, centromeric region TAS
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008278 cohesin complex IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016363 nuclear matrix IDA
 cellular_componentGO:0097431 mitotic spindle pole IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Meiotic synapsis
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Cohesin Loading onto Chromatin
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / complex






 

1 s.

 
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