ENSG00000102189


Homo sapiens

Features
Gene ID: ENSG00000102189
  
Biological name :EEA1
  
Synonyms : early endosome antigen 1 / EEA1 / Q15075
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q22
Gene start: 92770637
Gene end: 92929331
  
Corresponding Affymetrix probe sets: 204840_s_at (Human Genome U133 Plus 2.0 Array)   204841_s_at (Human Genome U133 Plus 2.0 Array)   225885_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317955
Ensembl peptide - ENSP00000394312
Ensembl peptide - ENSP00000446785
Ensembl peptide - ENSP00000449682
RefSeq - XM_017020018
RefSeq - NM_003566
RefSeq - XM_011538814
RefSeq - XM_011538815
RefSeq Peptide - NP_003557
swissprot - Q15075
swissprot - F8W119
swissprot - F8WE79
swissprot - F8VUZ7
Ensembl - ENSG00000102189
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eea1ENSDARG00000062868Danio rerio
 EEA1ENSGALG00000011280Gallus gallus
 Eea1ENSMUSG00000036499Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FYCO1 / Q9BQS8 / FYVE and coiled-coil domain containing 1ENSG0000016382016
RUFY4 / Q6ZNE9 / RUN and FYVE domain containing 4ENSG000001882827


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IMP
 biological_processGO:0006906 vesicle fusion IMP
 biological_processGO:0016189 synaptic vesicle to endosome fusion TAS
 biological_processGO:0039694 viral RNA genome replication IMP
 biological_processGO:0045022 early endosome to late endosome transport NAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005969 serine-pyruvate aminotransferase complex IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0019897 extrinsic component of plasma membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0044308 axonal spine IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding NAS
 molecular_functionGO:0005545 1-phosphatidylinositol binding TAS
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0030742 GTP-dependent protein binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 9 (TLR9) Cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000102189 EEA1 / Q15075 / early endosome antigen 1  / complex






 

1 s.

 
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