ENSMUSG00000036499


Mus musculus

Features
Gene ID: ENSMUSG00000036499
  
Biological name :Eea1
  
Synonyms : Early endosome antigen 1 / Eea1 / Q8BL66
  
Possible biological names infered from orthology : Q15075
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C2
Gene start: 95940650
Gene end: 96045518
  
Corresponding Affymetrix probe sets: 10365933 (MoGene1.0st)   1438045_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151703
Ensembl peptide - ENSMUSP00000061493
Ensembl peptide - ENSMUSP00000151611
NCBI entrez gene - 216238     See in Manteia.
MGI - MGI:2442192
RefSeq - XM_006513525
RefSeq - NM_001001932
RefSeq - XM_006513522
RefSeq - XM_006513523
RefSeq - XM_006513524
RefSeq Peptide - NP_001001932
swissprot - A0A1W2P7K1
swissprot - A0A1W2P7A6
swissprot - Q8BL66
Ensembl - ENSMUSG00000036499
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eea1ENSDARG00000062868Danio rerio
 EEA1ENSGALG00000011280Gallus gallus
 EEA1ENSG00000102189Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fyco1 / Q8VDC1 / FYVE and coiled-coil domain-containing protein 1 / Q9BQS8* / FYVE and coiled-coil domain containing 1*ENSMUSG0000002524116
Rufy4 / Q3TYX8 / RUN and FYVE domain-containing protein 4 / Q6ZNE9* / RUN and FYVE domain containing 4*ENSMUSG000000618156


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006906 vesicle fusion IEA
 biological_processGO:0039694 viral RNA genome replication IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005969 serine-pyruvate aminotransferase complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0044308 axonal spine IDA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005545 1-phosphatidylinositol binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Toll Like Receptor 9 (TLR9) Cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000036499 Eea1 / Q8BL66 / Early endosome antigen 1 / Q15075*  / complex






 

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contact: otassy@igbmc.fr