ENSG00000102858


Homo sapiens

Features
Gene ID: ENSG00000102858
  
Biological name :MGRN1
  
Synonyms : mahogunin ring finger 1 / MGRN1 / O60291
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 4616493
Gene end: 4690974
  
Corresponding Affymetrix probe sets: 212576_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468171
Ensembl peptide - ENSP00000467414
Ensembl peptide - ENSP00000468819
Ensembl peptide - ENSP00000262370
Ensembl peptide - ENSP00000382487
Ensembl peptide - ENSP00000393311
Ensembl peptide - ENSP00000443810
Ensembl peptide - ENSP00000464811
Ensembl peptide - ENSP00000465249
Ensembl peptide - ENSP00000465860
NCBI entrez gene - 23295     See in Manteia.
OMIM - 607559
RefSeq - XM_017023093
RefSeq - NM_001142291
RefSeq - NM_015246
RefSeq - XM_005255217
RefSeq - XM_005255218
RefSeq - XM_005255219
RefSeq - XM_005255220
RefSeq - XM_005255221
RefSeq - XM_011522441
RefSeq - XM_017023091
RefSeq - XM_017023092
RefSeq - NM_001142289
RefSeq - NM_001142290
RefSeq Peptide - NP_001135762
RefSeq Peptide - NP_001135763
RefSeq Peptide - NP_056061
RefSeq Peptide - NP_001135761
swissprot - B4DR12
swissprot - K7EIM7
swissprot - O60291
swissprot - K7EJN3
swissprot - K7EPJ5
swissprot - K7ERA1
Ensembl - ENSG00000102858
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mgrn1aENSDARG00000100072Danio rerio
 mgrn1bENSDARG00000004796Danio rerio
 MGRN1ENSGALG00000037492Gallus gallus
 Mgrn1ENSMUSG00000022517Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96PX1 / RNF157 / ring finger protein 157ENSG0000014157653


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006513 protein monoubiquitination IMP
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043951 negative regulation of cAMP-mediated signaling IDA
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0045879 negative regulation of smoothened signaling pathway ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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