ENSG00000102910


Homo sapiens

Features
Gene ID: ENSG00000102910
  
Biological name :LONP2
  
Synonyms : LONP2 / lon peptidase 2, peroxisomal / Q86WA8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q12.1
Gene start: 48244296
Gene end: 48363122
  
Corresponding Affymetrix probe sets: 221833_at (Human Genome U133 Plus 2.0 Array)   221834_at (Human Genome U133 Plus 2.0 Array)   223098_s_at (Human Genome U133 Plus 2.0 Array)   223099_s_at (Human Genome U133 Plus 2.0 Array)   229663_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455633
Ensembl peptide - ENSP00000455297
Ensembl peptide - ENSP00000457841
Ensembl peptide - ENSP00000285737
Ensembl peptide - ENSP00000415983
Ensembl peptide - ENSP00000445426
NCBI entrez gene - 83752     See in Manteia.
OMIM - 617774
RefSeq - XM_017023756
RefSeq - NM_001300948
RefSeq - NM_031490
RefSeq - XM_017023755
RefSeq Peptide - NP_113678
RefSeq Peptide - NP_001287877
swissprot - H3BUW8
swissprot - Q86WA8
swissprot - H3BPF7
swissprot - H3BQ67
swissprot - E7EN44
Ensembl - ENSG00000102910
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lonp2ENSDARG00000101438Danio rerio
 LONP2ENSGALG00000003942Gallus gallus
 Lonp2ENSMUSG00000047866Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LONP1 / P36776 / lon peptidase 1, mitochondrialENSG0000019636534


Protein motifs (from Interpro)
Interpro ID Name
 IPR003111  Lon, substrate-binding domain
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR004815  Lon protease, bacterial/eukaryotic-type
 IPR008268  Peptidase S16, active site
 IPR008269  Peptidase S16, Lon proteolytic domain
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR015947  PUA-like superfamily
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027065  Lon protease
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027501  Lon protease homologue 2, peroxisomal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006515 protein quality control for misfolded or incompletely synthesized proteins IEA
 biological_processGO:0006625 protein targeting to peroxisome IMP
 biological_processGO:0007031 peroxisome organization NAS
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0016485 protein processing IMP
 biological_processGO:0030163 protein catabolic process IEA
 biological_processGO:0031998 regulation of fatty acid beta-oxidation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005782 peroxisomal matrix IBA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0004176 ATP-dependent peptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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