ENSMUSG00000047866


Mus musculus

Features
Gene ID: ENSMUSG00000047866
  
Biological name :Lonp2
  
Synonyms : Lonp2 / Lon protease homolog 2, peroxisomal / Q9DBN5
  
Possible biological names infered from orthology : lon peptidase 2, peroxisomal / Q86WA8
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C3
Gene start: 86624043
Gene end: 86723873
  
Corresponding Affymetrix probe sets: 10573675 (MoGene1.0st)   1436655_at (Mouse Genome 430 2.0 Array)   1442258_at (Mouse Genome 430 2.0 Array)   1459784_x_at (Mouse Genome 430 2.0 Array)   1460178_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034141
Ensembl peptide - ENSMUSP00000113381
Ensembl peptide - ENSMUSP00000113834
Ensembl peptide - ENSMUSP00000118737
Ensembl peptide - ENSMUSP00000127938
NCBI entrez gene - 66887     See in Manteia.
MGI - MGI:1914137
RefSeq - NM_001168591
RefSeq - NM_025827
RefSeq Peptide - NP_001162063
RefSeq Peptide - NP_080103
swissprot - Q8BK80
swissprot - Q9DBN5
Ensembl - ENSMUSG00000047866
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lonp2ENSDARG00000101438Danio rerio
 LONP2ENSGALG00000003942Gallus gallus
 LONP2ENSG00000102910Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lonp1 / Q8CGK3 / Lon protease homolog, mitochondrial / P36776* / lon peptidase 1, mitochondrial*ENSMUSG0000004116834


Protein motifs (from Interpro)
Interpro ID Name
 IPR003111  Lon, substrate-binding domain
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR004815  Lon protease, bacterial/eukaryotic-type
 IPR008268  Peptidase S16, active site
 IPR008269  Peptidase S16, Lon proteolytic domain
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR015947  PUA-like superfamily
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027065  Lon protease
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027501  Lon protease homologue 2, peroxisomal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006515 protein quality control for misfolded or incompletely synthesized proteins IEA
 biological_processGO:0006625 protein targeting to peroxisome IBA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0016485 protein processing IBA
 biological_processGO:0030163 protein catabolic process IEA
 biological_processGO:0031998 regulation of fatty acid beta-oxidation ISO
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005782 peroxisomal matrix ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002020 protease binding ISO
 molecular_functionGO:0004176 ATP-dependent peptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO


Pathways (from Reactome)
Pathway description
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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