ENSG00000104343


Homo sapiens

Features
Gene ID: ENSG00000104343
  
Biological name :UBE2W
  
Synonyms : Q96B02 / UBE2W / ubiquitin conjugating enzyme E2 W
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q21.11
Gene start: 73780097
Gene end: 73878910
  
Corresponding Affymetrix probe sets: 1555217_at (Human Genome U133 Plus 2.0 Array)   1562458_at (Human Genome U133 Plus 2.0 Array)   218521_s_at (Human Genome U133 Plus 2.0 Array)   222656_at (Human Genome U133 Plus 2.0 Array)   222657_s_at (Human Genome U133 Plus 2.0 Array)   241887_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429136
Ensembl peptide - ENSP00000473561
Ensembl peptide - ENSP00000430254
Ensembl peptide - ENSP00000397453
Ensembl peptide - ENSP00000414771
Ensembl peptide - ENSP00000428813
Ensembl peptide - ENSP00000428835
NCBI entrez gene - 55284     See in Manteia.
OMIM - 614277
RefSeq - NM_001001481
RefSeq - NM_001271015
RefSeq - NM_018299
RefSeq Peptide - NP_001001481
RefSeq Peptide - NP_060769
RefSeq Peptide - NP_001257944
swissprot - X6REH9
swissprot - H0YB73
swissprot - Q96B02
swissprot - E5RG25
Ensembl - ENSG00000104343
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ube2wENSMUSG00000025939Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC022826.2ENSG0000025867775
UBE2C / O00762 / ubiquitin conjugating enzyme E2 CENSG0000017506327


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006513 protein monoubiquitination IMP
 biological_processGO:0006515 protein quality control for misfolded or incompletely synthesized proteins ISS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0070979 protein K11-linked ubiquitination IDA
 biological_processGO:0071218 cellular response to misfolded protein ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr