ENSG00000104765


Homo sapiens

Features
Gene ID: ENSG00000104765
  
Biological name :BNIP3L
  
Synonyms : BCL2 interacting protein 3 like / BNIP3L / O60238
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.2
Gene start: 26382898
Gene end: 26505636
  
Corresponding Affymetrix probe sets: 221478_at (Human Genome U133 Plus 2.0 Array)   221479_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370003
Ensembl peptide - ENSP00000429171
Ensembl peptide - ENSP00000429851
Ensembl peptide - ENSP00000429698
Ensembl peptide - ENSP00000428597
Ensembl peptide - ENSP00000428919
NCBI entrez gene - 665     See in Manteia.
OMIM - 605368
RefSeq - NM_004331
RefSeq - XM_005273617
RefSeq - NM_001330491
RefSeq Peptide - NP_001317420
RefSeq Peptide - NP_004322
swissprot - H0YBC7
swissprot - O60238
swissprot - Q6IBV1
swissprot - E5RFE9
Ensembl - ENSG00000104765
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bnip3laENSDARG00000025468Danio rerio
 bnip3lbENSDARG00000028067Danio rerio
 BNIP3LENSGALG00000043405Gallus gallus
 Bnip3lENSMUSG00000022051Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BNIP3 / Q12983 / BCL2 interacting protein 3ENSG0000017617153


Protein motifs (from Interpro)
Interpro ID Name
 IPR010548  BNIP3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010917 negative regulation of mitochondrial membrane potential IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016239 positive regulation of macroautophagy IGI
 biological_processGO:0035694 mitochondrial protein catabolic process IMP
 biological_processGO:0035794 positive regulation of mitochondrial membrane permeability IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0060548 negative regulation of cell death IGI
 biological_processGO:0071456 cellular response to hypoxia IGI
 biological_processGO:0097345 mitochondrial outer membrane permeabilization IBA
 biological_processGO:1903146 regulation of autophagy of mitochondrion IEA
 biological_processGO:1903214 regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005740 mitochondrial envelope IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0031224 intrinsic component of membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005521 lamin binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115107 Q658P3 / STEAP3 / STEAP3 metalloreductase  / reaction / complex






 

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